Daily Papers

Transformers show remarkable versatility across domains, suggesting the existence of inductive biases beneficial across modalities. In this work, we explore a new way to instil such generic biases in vision transformers (ViTs) by pretraining on procedurally-generated data devoid of visual or semantic content. We generate this data with simple algorithms such as formal grammars, so the results bear no relationship to either natural or synthetic images. We use this procedurally-generated data to pretrain ViTs in a warm-up phase that bypasses their visual patch embedding mechanisms, thus encouraging the models to internalise abstract computational priors. When followed by standard image-based training, this warm-up significantly improves data efficiency, convergence speed, and downstream performance. On ImageNet-1k for example, allocating just 1% of the training budget to procedural data improves final accuracy by over 1.7%. In terms of its effect on performance, 1% procedurally generated data is thus equivalent to 28% of the ImageNet-1k data. These findings suggest a promising path toward new data-efficient and domain-agnostic pretraining strategies.

Generative molecular design is shaped by simple proxy benchmarks for drug-like properties and models pretrained on large pharmaceutical datasets. This combination yields strong benchmark metrics but limits transferability to domains structurally distinct from drug discovery. To overcome this limitation and drive discovery toward real, scientifically grounded targets, we introduce the Nanotechnology Molecular Optimization (NMO) Benchmark, which bridges machine learning (ML) and quantum materials science. NMO acts simultaneously as a rigorous testbed for the ML community and a discovery engine for nanotechnology research. The suite replaces proxy oracles with quantum simulations and introduces strict protocols that prioritize scientific utility over leaderboard-oriented overfitting. The physics-based NMO tasks impose hard structural constraints and rugged fitness landscapes, posing fundamentally new requirements on generative models. Notably, advanced molecular optimization methods underperform much simpler approaches on the NMO tasks. We develop a new baseline method identifying the critical components to solve the NMO tasks, including a novel representation for modeling structural constraints and a domain-agnostic pretraining strategy to eliminate pharmaceutical dataset bias. Our results surpass state-of-the-art physical properties and reveal previously unknown structural motifs, offering new insights for the nanotechnology community and demonstrating that ML can drive genuine scientific discovery.

Existing foundation models (FMs) in the medical domain often require extensive fine-tuning or rely on training resource-intensive decoders, while many existing encoders are pretrained with objectives biased toward specific tasks. This illustrates a need for a strong, task-agnostic foundation model that requires minimal fine-tuning beyond feature extraction. In this work, we introduce a suite of task-agnostic pretraining of CT foundation models (TAP-CT): a simple yet effective adaptation of Vision Transformers (ViTs) and DINOv2 for volumetric data, enabling scalable self-supervised pretraining directly on 3D CT volumes. Our approach incorporates targeted modifications to patch embeddings, positional encodings, and volumetric augmentations, making the architecture depth-aware while preserving the simplicity of the underlying architectures. We show that large-scale 3D pretraining on an extensive in-house CT dataset (105K volumes) yields stable, robust frozen representations that generalize strongly across downstream tasks. To promote transparency and reproducibility, and to establish a powerful, low-resource baseline for future research in medical imaging, we will release all pretrained models, experimental configurations, and downstream benchmark code at https://huggingface.co/fomofo/tap-ct-b-3d.

Pretraining large language models (LLMs) on high-quality, structured data such as mathematics and code substantially enhances reasoning capabilities. However, existing math-focused datasets built from Common Crawl suffer from degraded quality due to brittle extraction heuristics, lossy HTML-to-text conversion, and the failure to reliably preserve mathematical structure. In this work, we introduce Nemotron-CC-Math, a large-scale, high-quality mathematical corpus constructed from Common Crawl using a novel, domain-agnostic pipeline specifically designed for robust scientific text extraction. Unlike previous efforts, our pipeline recovers math across various formats (e.g., MathJax, KaTeX, MathML) by leveraging layout-aware rendering with lynx and a targeted LLM-based cleaning stage. This approach preserves the structural integrity of equations and code blocks while removing boilerplate, standardizing notation into LaTeX representation, and correcting inconsistencies. We collected a large, high-quality math corpus, namely Nemotron-CC-Math-3+ (133B tokens) and Nemotron-CC-Math-4+ (52B tokens). Notably, Nemotron-CC-Math-4+ not only surpasses all prior open math datasets-including MegaMath, FineMath, and OpenWebMath-but also contains 5.5 times more tokens than FineMath-4+, which was previously the highest-quality math pretraining dataset. When used to pretrain a Nemotron-T 8B model, our corpus yields +4.8 to +12.6 gains on MATH and +4.6 to +14.3 gains on MBPP+ over strong baselines, while also improving general-domain performance on MMLU and MMLU-Stem. We present the first pipeline to reliably extract scientific content--including math--from noisy web-scale data, yielding measurable gains in math, code, and general reasoning, and setting a new state of the art among open math pretraining corpora. To support open-source efforts, we release our code and datasets.

Learning visual representations of medical images (e.g., X-rays) is core to medical image understanding but its progress has been held back by the scarcity of human annotations. Existing work commonly relies on fine-tuning weights transferred from ImageNet pretraining, which is suboptimal due to drastically different image characteristics, or rule-based label extraction from the textual report data paired with medical images, which is inaccurate and hard to generalize. Meanwhile, several recent studies show exciting results from unsupervised contrastive learning from natural images, but we find these methods help little on medical images because of their high inter-class similarity. We propose ConVIRT, an alternative unsupervised strategy to learn medical visual representations by exploiting naturally occurring paired descriptive text. Our new method of pretraining medical image encoders with the paired text data via a bidirectional contrastive objective between the two modalities is domain-agnostic, and requires no additional expert input. We test ConVIRT by transferring our pretrained weights to 4 medical image classification tasks and 2 zero-shot retrieval tasks, and show that it leads to image representations that considerably outperform strong baselines in most settings. Notably, in all 4 classification tasks, our method requires only 10\% as much labeled training data as an ImageNet initialized counterpart to achieve better or comparable performance, demonstrating superior data efficiency.

Real-world model deployments demand strong performance on narrow domains where data is often scarce. Typically, practitioners finetune models to specialize them, but this risks overfitting to the domain and forgetting general knowledge. We study a simple strategy, specialized pretraining (SPT), where a small domain dataset, typically reserved for finetuning, is repeated starting from pretraining as a fraction of the total tokens. Across three specialized domains (ChemPile, MusicPile, and ProofPile), SPT improves domain performance and preserves general capabilities after finetuning compared to standard pretraining. In our experiments, SPT reduces the pretraining tokens needed to reach a given domain performance by up to 1.75x. These gains grow when the target domain is underrepresented in the pretraining corpus: on domains far from web text, a 1B SPT model outperforms a 3B standard pretrained model. Beyond these empirical gains, we derive overfitting scaling laws to guide practitioners in selecting the optimal domain-data repetition for a given pretraining compute budget. Our observations reveal the finetuner's fallacy: while finetuning may appear to be the cheapest path to domain adaptation, introducing specialized domain data during pretraining stretches its utility. SPT yields better specialized domain performance (via reduced overfitting across repeated exposures) and better general domain performance (via reduced forgetting during finetuning), ultimately achieving stronger results with fewer parameters and less total compute when amortized over inference. To get the most out of domain data, incorporate it as early in training as possible.

Self-supervised learning of speech representations has been a very active research area but most work is focused on a single domain such as read audio books for which there exist large quantities of labeled and unlabeled data. In this paper, we explore more general setups where the domain of the unlabeled data for pre-training data differs from the domain of the labeled data for fine-tuning, which in turn may differ from the test data domain. Our experiments show that using target domain data during pre-training leads to large performance improvements across a variety of setups. On a large-scale competitive setup, we show that pre-training on unlabeled in-domain data reduces the gap between models trained on in-domain and out-of-domain labeled data by 66%-73%. This has obvious practical implications since it is much easier to obtain unlabeled target domain data than labeled data. Moreover, we find that pre-training on multiple domains improves generalization performance on domains not seen during training. Code and models will be made available at https://github.com/pytorch/fairseq.

Pretraining large neural language models, such as BERT, has led to impressive gains on many natural language processing (NLP) tasks. However, most pretraining efforts focus on general domain corpora, such as newswire and Web. A prevailing assumption is that even domain-specific pretraining can benefit by starting from general-domain language models. In this paper, we challenge this assumption by showing that for domains with abundant unlabeled text, such as biomedicine, pretraining language models from scratch results in substantial gains over continual pretraining of general-domain language models. To facilitate this investigation, we compile a comprehensive biomedical NLP benchmark from publicly-available datasets. Our experiments show that domain-specific pretraining serves as a solid foundation for a wide range of biomedical NLP tasks, leading to new state-of-the-art results across the board. Further, in conducting a thorough evaluation of modeling choices, both for pretraining and task-specific fine-tuning, we discover that some common practices are unnecessary with BERT models, such as using complex tagging schemes in named entity recognition (NER). To help accelerate research in biomedical NLP, we have released our state-of-the-art pretrained and task-specific models for the community, and created a leaderboard featuring our BLURB benchmark (short for Biomedical Language Understanding & Reasoning Benchmark) at https://aka.ms/BLURB.

Current state-of-the-art dialogue systems heavily rely on extensive training datasets. However, challenges arise in domains where domain-specific training datasets are insufficient or entirely absent. To tackle this challenge, we propose a novel data Augmentation framework for Multi-Domain Dialogue Generation, referred to as AMD^2G. The AMD^2G framework consists of a data augmentation process and a two-stage training approach: domain-agnostic training and domain adaptation training. We posit that domain corpora are a blend of domain-agnostic and domain-specific features, with certain representation patterns shared among diverse domains. Domain-agnostic training aims to enable models to learn these common expressive patterns. To construct domain-agnostic dialogue corpora, we employ a \textbf{de-domaining} data processing technique used to remove domain-specific features. By mitigating the effects of domain-specific features, the model trained on the de-domained corpora can effectively learn common expression patterns in different domains. Subsequently, we adapt the learned domain-agnostic features to the target domain through domain adaptation training. We conduct experiments on Chinese dialogue datasets from five different domains and show that AMD^2G achieves superior performance compared to both direct training on the target domain corpus and collective training on all five domain corpora. Our work underscores AMD^2G as a viable alternative solution for low-resource multi-domain dialogue generation. Code and data associated with our work are available on GitHub repository^{text 1}.

Continued pre-training of small language models offers a promising path for domain adaptation with limited computational resources. I've investigated this approach within educational domains, evaluating it as a resource-efficient alternative to training models from scratch. Using a 125M parameter model, I demonstrate significant performance improvements through incremental training on 400 million tokens, followed by further training to reach 1 billion tokens. My approach includes comprehensive data preprocessing, memory-optimized training configurations, and benchmark-based evaluation. Results show notable gains in knowledge-intensive tasks (MMLU +8.1%) and contextual understanding (HellaSwag +7.6%), while revealing educational domain specialization trade-offs. I analyze token efficiency, catastrophic forgetting mitigation strategies, and scaling patterns. My findings suggest that thoughtful preprocessing and training methodologies enable meaningful improvements in language model capabilities even with constrained computational resources, opening pathways for domain-specific adaptation of smaller language models.

Language models pretrained on text from a wide variety of sources form the foundation of today's NLP. In light of the success of these broad-coverage models, we investigate whether it is still helpful to tailor a pretrained model to the domain of a target task. We present a study across four domains (biomedical and computer science publications, news, and reviews) and eight classification tasks, showing that a second phase of pretraining in-domain (domain-adaptive pretraining) leads to performance gains, under both high- and low-resource settings. Moreover, adapting to the task's unlabeled data (task-adaptive pretraining) improves performance even after domain-adaptive pretraining. Finally, we show that adapting to a task corpus augmented using simple data selection strategies is an effective alternative, especially when resources for domain-adaptive pretraining might be unavailable. Overall, we consistently find that multi-phase adaptive pretraining offers large gains in task performance.

Recent breakthroughs in scale have enabled the emergence of powerful generative language models, and the ability to fine-tune these models on various tasks by casting them into prompts or instructions. In this landscape, the problem of Unsupervised Domain Adaptation (UDA), or the problem of leveraging knowledge from a labeled source domain to an unlabeled target domain, has been left behind, with recent UDA methods still addressing discriminative classification. In particular, two popular UDA approaches, involving Continued Pre-Training (CPT) and learning domain invariant representations, have been under-explored in the generative setting, signaling a gap. In this work, we evaluate the utility of CPT for generative UDA. We first perform an empirical evaluation to measure the trade-offs between CPT and strong methods promoting domain invariance. We further evaluate how well the benefits of CPT extend to different architectures, tuning methods and data regimes. We then motivate the use of CPT by studying to what degree it benefits classification performance on the target domain. Finally, we attempt to understand the mechanism behind which CPT improves classification performance on the unlabeled target domain. Our findings suggest that a implicitly learns the downstream task while predicting masked words informative to that task. Our work connects the body of UDA research with that of instruction tuning, enabling an initial step towards a wider applicability of modern language models.

We consider unsupervised domain adaptation (UDA), where labeled data from a source domain (e.g., photographs) and unlabeled data from a target domain (e.g., sketches) are used to learn a classifier for the target domain. Conventional UDA methods (e.g., domain adversarial training) learn domain-invariant features to improve generalization to the target domain. In this paper, we show that contrastive pre-training, which learns features on unlabeled source and target data and then fine-tunes on labeled source data, is competitive with strong UDA methods. However, we find that contrastive pre-training does not learn domain-invariant features, diverging from conventional UDA intuitions. We show theoretically that contrastive pre-training can learn features that vary subtantially across domains but still generalize to the target domain, by disentangling domain and class information. Our results suggest that domain invariance is not necessary for UDA. We empirically validate our theory on benchmark vision datasets.

The coverage and composition of the pretraining data significantly impacts the generalization ability of Large Language Models (LLMs). Despite its importance, recent LLMs still rely on heuristics and trial and error to increase or reduce the influence of data-domains. We propose DOmain reweighting with Generalization Estimation (DoGE), which optimizes the probability of sampling from each domain (domain weights) in a principled way. Our approach is a two-stage process consisting of (i) training a proxy model to obtain domain weights using a bi-level optimization algorithm; (ii) training a larger base model by sampling training domains according to the learned domain weights. In our experiments, we extensively show how DoGE improves the generalization of the base model to any target data mixture. On the SlimPajama dataset, our base model gets better perplexity and few-shot reasoning accuracies across 6 tasks compared to baseline methods. Moreover, aiming to generalize to out-of-domain target tasks, which is unseen in the pretraining corpus (OOD domain), DoGE can effectively identify inter-domain dependencies, and consistently achieves better test perplexity on the target domain.

Although pre-trained language models have exhibited great flexibility and versatility with prompt-based few-shot learning, they suffer from the extensive parameter size and limited applicability for inference. Recent studies have suggested that PLMs be used as dataset generators and a tiny task-specific model be trained to achieve efficient inference. However, their applicability to various domains is limited because they tend to generate domain-specific datasets. In this work, we propose a novel approach to universal domain generalization that generates a dataset regardless of the target domain. This allows for generalization of the tiny task model to any domain that shares the label space, thus enhancing the real-world applicability of the dataset generation paradigm. Our experiments indicate that the proposed method accomplishes generalizability across various domains while using a parameter set that is orders of magnitude smaller than PLMs.

Domain Generalization aims to develop models that can generalize to novel and unseen data distributions. In this work, we study how model architectures and pre-training objectives impact feature richness and propose a method to effectively leverage them for domain generalization. Specifically, given a pre-trained feature space, we first discover latent domain structures, referred to as pseudo-domains, that capture domain-specific variations in an unsupervised manner. Next, we augment existing classifiers with these complementary pseudo-domain representations making them more amenable to diverse unseen test domains. We analyze how different pre-training feature spaces differ in the domain-specific variances they capture. Our empirical studies reveal that features from diffusion models excel at separating domains in the absence of explicit domain labels and capture nuanced domain-specific information. On 5 datasets, we show that our very simple framework improves generalization to unseen domains by a maximum test accuracy improvement of over 4% compared to the standard baseline Empirical Risk Minimization (ERM). Crucially, our method outperforms most algorithms that access domain labels during training.

Supervised fine-tuning (SFT) is widely used to align large language models (LLMs) with information extraction (IE) tasks, such as named entity recognition (NER). However, annotating such fine-grained labels and training domain-specific models is costly. Existing works typically train a unified model across multiple domains, but such approaches lack adaptation and scalability since not all training data benefits target domains and scaling trained models remains challenging. We propose the SaM framework, which dynamically Selects and Merges expert models at inference time. Specifically, for a target domain, we select domain-specific experts pre-trained on existing domains based on (i) domain similarity to the target domain and (ii) performance on sampled instances, respectively. The experts are then merged to create task-specific models optimized for the target domain. By dynamically merging experts beneficial to target domains, we improve generalization across various domains without extra training. Additionally, experts can be added or removed conveniently, leading to great scalability. Extensive experiments on multiple benchmarks demonstrate our framework's effectiveness, which outperforms the unified model by an average of 10%. We further provide insights into potential improvements, practical experience, and extensions of our framework.

In Information Retrieval, and more generally in Natural Language Processing, adapting models to specific domains is conducted through fine-tuning. Despite the successes achieved by this method and its versatility, the need for human-curated and labeled data makes it impractical to transfer to new tasks, domains, and/or languages when training data doesn't exist. Using the model without training (zero-shot) is another option that however suffers an effectiveness cost, especially in the case of first-stage retrievers. Numerous research directions have emerged to tackle these issues, most of them in the context of adapting to a task or a language. However, the literature is scarcer for domain (or topic) adaptation. In this paper, we address this issue of cross-topic discrepancy for a sparse first-stage retriever by transposing a method initially designed for language adaptation. By leveraging pre-training on the target data to learn domain-specific knowledge, this technique alleviates the need for annotated data and expands the scope of domain adaptation. Despite their relatively good generalization ability, we show that even sparse retrievers can benefit from our simple domain adaptation method.

Continual domain shift poses a significant challenge in real-world applications, particularly in situations where labeled data is not available for new domains. The challenge of acquiring knowledge in this problem setting is referred to as unsupervised continual domain shift learning. Existing methods for domain adaptation and generalization have limitations in addressing this issue, as they focus either on adapting to a specific domain or generalizing to unseen domains, but not both. In this paper, we propose Complementary Domain Adaptation and Generalization (CoDAG), a simple yet effective learning framework that combines domain adaptation and generalization in a complementary manner to achieve three major goals of unsupervised continual domain shift learning: adapting to a current domain, generalizing to unseen domains, and preventing forgetting of previously seen domains. Our approach is model-agnostic, meaning that it is compatible with any existing domain adaptation and generalization algorithms. We evaluate CoDAG on several benchmark datasets and demonstrate that our model outperforms state-of-the-art models in all datasets and evaluation metrics, highlighting its effectiveness and robustness in handling unsupervised continual domain shift learning.

Pretraining datasets for large language models (LLMs) have grown to trillions of tokens composed of large amounts of CommonCrawl (CC) web scrape along with smaller, domain-specific datasets. It is expensive to understand the impact of these domain-specific datasets on model capabilities as training at large FLOP scales is required to reveal significant changes to difficult and emergent benchmarks. Given the increasing cost of experimenting with pretraining data, how does one determine the optimal balance between the diversity in general web scrapes and the information density of domain specific data? In this work, we show how to leverage the smaller domain specific datasets by upsampling them relative to CC at the end of training to drive performance improvements on difficult benchmarks. This simple technique allows us to improve up to 6.90 pp on MMLU, 8.26 pp on GSM8K, and 6.17 pp on HumanEval relative to the base data mix for a 7B model trained for 1 trillion (T) tokens, thus rivaling Llama-2 (7B)x2014a model trained for twice as long. We experiment with ablating the duration of domain upsampling from 5% to 30% of training and find that 10% to 20% percent is optimal for navigating the tradeoff between general language modeling capabilities and targeted benchmarks. We also use domain upsampling to characterize at scale the utility of individual datasets for improving various benchmarks by removing them during this final phase of training. This tool opens up the ability to experiment with the impact of different pretraining datasets at scale, but at an order of magnitude lower cost compared to full pretraining runs.

In the realm of self-supervised learning (SSL), conventional wisdom has gravitated towards the utility of massive, general domain datasets for pretraining robust backbones. In this paper, we challenge this idea by exploring if it is possible to bridge the scale between general-domain datasets and (traditionally smaller) domain-specific datasets to reduce the current performance gap. More specifically, we propose Precision at Scale (PaS), a novel method for the autonomous creation of domain-specific datasets on-demand. The modularity of the PaS pipeline enables leveraging state-of-the-art foundational and generative models to create a collection of images of any given size belonging to any given domain with minimal human intervention. Extensive analysis in two complex domains, proves the superiority of PaS datasets over existing traditional domain-specific datasets in terms of diversity, scale, and effectiveness in training visual transformers and convolutional neural networks. Most notably, we prove that automatically generated domain-specific datasets lead to better pretraining than large-scale supervised datasets such as ImageNet-1k and ImageNet-21k. Concretely, models trained on domain-specific datasets constructed by PaS pipeline, beat ImageNet-1k pretrained backbones by at least 12% in all the considered domains and classification tasks and lead to better food domain performance than supervised ImageNet-21k pretrain while being 12 times smaller. Code repository: https://github.com/jesusmolrdv/Precision-at-Scale/

Training keyphrase generation (KPG) models require a large amount of annotated data, which can be prohibitively expensive and often limited to specific domains. In this study, we first demonstrate that large distribution shifts among different domains severely hinder the transferability of KPG models. We then propose a three-stage pipeline, which gradually guides KPG models' learning focus from general syntactical features to domain-related semantics, in a data-efficient manner. With Domain-general Phrase pre-training, we pre-train Sequence-to-Sequence models with generic phrase annotations that are widely available on the web, which enables the models to generate phrases in a wide range of domains. The resulting model is then applied in the Transfer Labeling stage to produce domain-specific pseudo keyphrases, which help adapt models to a new domain. Finally, we fine-tune the model with limited data with true labels to fully adapt it to the target domain. Our experiment results show that the proposed process can produce good-quality keyphrases in new domains and achieve consistent improvements after adaptation with limited in-domain annotated data. All code and datasets are available at https://github.com/memray/OpenNMT-kpg-release.

Domain shift refers to the well known problem that a model trained in one source domain performs poorly when applied to a target domain with different statistics. {Domain Generalization} (DG) techniques attempt to alleviate this issue by producing models which by design generalize well to novel testing domains. We propose a novel {meta-learning} method for domain generalization. Rather than designing a specific model that is robust to domain shift as in most previous DG work, we propose a model agnostic training procedure for DG. Our algorithm simulates train/test domain shift during training by synthesizing virtual testing domains within each mini-batch. The meta-optimization objective requires that steps to improve training domain performance should also improve testing domain performance. This meta-learning procedure trains models with good generalization ability to novel domains. We evaluate our method and achieve state of the art results on a recent cross-domain image classification benchmark, as well demonstrating its potential on two classic reinforcement learning tasks.

This paper studies the evolving domain of Continual Learning (CL) in large language models (LLMs), with a focus on developing strategies for efficient and sustainable training. Our primary emphasis is on continual domain-adaptive pretraining, a process designed to equip LLMs with the ability to integrate new information from various domains while retaining previously learned knowledge and enhancing cross-domain knowledge transfer without relying on domain-specific identification. Unlike previous studies, which mostly concentrate on a limited selection of tasks or domains and primarily aim to address the issue of forgetting, our research evaluates the adaptability and capabilities of LLMs to changing data landscapes in practical scenarios. To this end, we introduce a new benchmark designed to measure the adaptability of LLMs to these evolving data environments, offering a comprehensive framework for evaluation. We examine the impact of model size on learning efficacy and forgetting, as well as how the progression and similarity of emerging domains affect the knowledge transfer within these models. Our findings uncover several key insights: (i) when the sequence of domains shows semantic similarity, continual pretraining enables LLMs to better specialize in the current domain compared to stand-alone fine-tuning, (ii) training across a diverse range of domains enhances both backward and forward knowledge transfer, and (iii) smaller models are particularly sensitive to continual pretraining, showing the most significant rates of both forgetting and learning. We posit that our research marks a shift towards establishing a more realistic benchmark for investigating CL in LLMs, and has the potential to play a key role in guiding the direction of future research in the field.

Domain-adaptive continual pretraining (DAPT) is a state-of-the-art technique that further trains a language model (LM) on its pretraining task, e.g., language masking. Although popular, it requires a significant corpus of domain-related data, which is difficult to obtain for specific domains in languages other than English, such as the process industry in the German language. This paper introduces an efficient approach called ICL-augmented pretraining or ICL-APT that leverages in-context learning (ICL) and k-nearest neighbors (kNN) to augment target data with domain-related and in-domain texts, significantly reducing GPU time while maintaining strong model performance. Our results show that this approach performs better than traditional DAPT by 3.5 of the average IR metrics (e.g., mAP, MRR, and nDCG) and requires almost 4 times less computing time, providing a cost-effective solution for industries with limited computational capacity. The findings highlight the broader applicability of this framework to other low-resource industries, making NLP-based solutions more accessible and feasible in production environments.

As the capabilities of language models continue to advance, it is conceivable that "one-size-fits-all" model will remain as the main paradigm. For instance, given the vast number of languages worldwide, many of which are low-resource, the prevalent practice is to pretrain a single model on multiple languages. In this paper, we add to the growing body of evidence that challenges this practice, demonstrating that monolingual pretraining on the target language significantly improves models already extensively trained on diverse corpora. More specifically, we further pretrain GPT-J and LLaMA models on Portuguese texts using 3% or less of their original pretraining budget. Few-shot evaluations on Poeta, a suite of 14 Portuguese datasets, reveal that our models outperform English-centric and multilingual counterparts by a significant margin. Our best model, Sabi\'a-65B, performs on par with GPT-3.5-turbo. By evaluating on datasets originally conceived in the target language as well as translated ones, we study the contributions of language-specific pretraining in terms of 1) capturing linguistic nuances and structures inherent to the target language, and 2) enriching the model's knowledge about a domain or culture. Our results indicate that the majority of the benefits stem from the domain-specific knowledge acquired through monolingual pretraining.

Pretraining is the preliminary and fundamental step in developing capable language models (LM). Despite this, pretraining data design is critically under-documented and often guided by empirically unsupported intuitions. To address this, we pretrain 28 1.5B parameter decoder-only models, training on data curated (1) at different times, (2) with varying toxicity and quality filters, and (3) with different domain compositions. First, we quantify the effect of pretraining data age. A temporal shift between evaluation data and pretraining data leads to performance degradation, which is not overcome by finetuning. Second, we explore the effect of quality and toxicity filters, showing a trade-off between performance on standard benchmarks and risk of toxic generations. Our findings indicate there does not exist a one-size-fits-all solution to filtering training data. We also find that the effects of different types of filtering are not predictable from text domain characteristics. Lastly, we empirically validate that the inclusion of heterogeneous data sources, like books and web, is broadly beneficial and warrants greater prioritization. These findings constitute the largest set of experiments to validate, quantify, and expose many undocumented intuitions about text pretraining, which we hope will help support more informed data-centric decisions in LM development.

While self-supervised learning has made rapid advances in natural language processing, it remains unclear when researchers should engage in resource-intensive domain-specific pretraining (domain pretraining). The law, puzzlingly, has yielded few documented instances of substantial gains to domain pretraining in spite of the fact that legal language is widely seen to be unique. We hypothesize that these existing results stem from the fact that existing legal NLP tasks are too easy and fail to meet conditions for when domain pretraining can help. To address this, we first present CaseHOLD (Case Holdings On Legal Decisions), a new dataset comprised of over 53,000+ multiple choice questions to identify the relevant holding of a cited case. This dataset presents a fundamental task to lawyers and is both legally meaningful and difficult from an NLP perspective (F1 of 0.4 with a BiLSTM baseline). Second, we assess performance gains on CaseHOLD and existing legal NLP datasets. While a Transformer architecture (BERT) pretrained on a general corpus (Google Books and Wikipedia) improves performance, domain pretraining (using corpus of approximately 3.5M decisions across all courts in the U.S. that is larger than BERT's) with a custom legal vocabulary exhibits the most substantial performance gains with CaseHOLD (gain of 7.2% on F1, representing a 12% improvement on BERT) and consistent performance gains across two other legal tasks. Third, we show that domain pretraining may be warranted when the task exhibits sufficient similarity to the pretraining corpus: the level of performance increase in three legal tasks was directly tied to the domain specificity of the task. Our findings inform when researchers should engage resource-intensive pretraining and show that Transformer-based architectures, too, learn embeddings suggestive of distinct legal language.

Source-free domain adaptation (SFDA) aims to adapt a source model trained on a fully-labeled source domain to an unlabeled target domain. Large-data pre-trained networks are used to initialize source models during source training, and subsequently discarded. However, source training can cause the model to overfit to source data distribution and lose applicable target domain knowledge. We propose to integrate the pre-trained network into the target adaptation process as it has diversified features important for generalization and provides an alternate view of features and classification decisions different from the source model. We propose to distil useful target domain information through a co-learning strategy to improve target pseudolabel quality for finetuning the source model. Evaluation on 4 benchmark datasets show that our proposed strategy improves adaptation performance and can be successfully integrated with existing SFDA methods. Leveraging modern pre-trained networks that have stronger representation learning ability in the co-learning strategy further boosts performance.

Large Language Models (LLMs) pre-trained on massive corpora have exhibited remarkable performance on various NLP tasks. However, applying these models to specific domains still poses significant challenges, such as lack of domain knowledge, limited capacity to leverage domain knowledge and inadequate adaptation to domain-specific data formats. Considering the exorbitant cost of training LLMs from scratch and the scarcity of annotated data within particular domains, in this work, we focus on domain-specific continual pre-training of LLMs using E-commerce domain as an exemplar. Specifically, we explore the impact of continual pre-training on LLMs employing unlabeled general and E-commercial corpora. Furthermore, we design a mixing strategy among different data sources to better leverage E-commercial semi-structured data. We construct multiple tasks to assess LLMs' few-shot In-context Learning ability and their zero-shot performance after instruction tuning in E-commerce domain. Experimental results demonstrate the effectiveness of continual pre-training of E-commerce LLMs and the efficacy of our devised data mixing strategy.

Large language models (LLMs) have demonstrated remarkable capabilities across diverse domains, yet their adaptation to specialized fields remains challenging, particularly for non-English languages. This study investigates domain-adaptive pre-training (DAPT) as a strategy for specializing small to mid-sized LLMs in the French biomedical domain through continued pre-training. We address two key research questions: the viability of specialized continued pre-training for domain adaptation and the relationship between domain-specific performance gains and general capability degradation. Our contributions include the release of a fully open-licensed French biomedical corpus suitable for commercial and open-source applications, the training and release of specialized French biomedical LLMs, and novel insights for DAPT implementation. Our methodology encompasses the collection and refinement of high-quality French biomedical texts, the exploration of causal language modeling approaches using DAPT, and conducting extensive comparative evaluations. Our results cast doubt on the efficacy of DAPT, in contrast to previous works, but we highlight its viability in smaller-scale, resource-constrained scenarios under the right conditions. Findings in this paper further suggest that model merging post-DAPT is essential to mitigate generalization trade-offs, and in some cases even improves performance on specialized tasks at which the DAPT was directed.

The performance emergence of large language models (LLMs) driven by data scaling laws makes the selection of pre-training data increasingly important. However, existing methods rely on limited heuristics and human intuition, lacking comprehensive and clear guidelines. To address this, we are inspired by ``reverse thinking'' -- prompting LLMs to self-identify which criteria benefit its performance. As its pre-training capabilities are related to perplexity (PPL), we derive 14 quality criteria from the causes of text perplexity anomalies and introduce 15 common application domains to support domain mixing. In this paper, we train a Data Manager (DataMan) to learn quality ratings and domain recognition from pointwise rating, and use it to annotate a 447B token pre-training corpus with 14 quality ratings and domain type. Our experiments validate our approach, using DataMan to select 30B tokens to train a 1.3B-parameter language model, demonstrating significant improvements in in-context learning (ICL), perplexity, and instruction-following ability over the state-of-the-art baseline. The best-performing model, based on the Overall Score l=5 surpasses a model trained with 50% more data using uniform sampling. We continue pre-training with high-rated, domain-specific data annotated by DataMan to enhance domain-specific ICL performance and thus verify DataMan's domain mixing ability. Our findings emphasize the importance of quality ranking, the complementary nature of quality criteria, and their low correlation with perplexity, analyzing misalignment between PPL and ICL performance. We also thoroughly analyzed our pre-training dataset, examining its composition, the distribution of quality ratings, and the original document sources.

Pre-training Transformers has shown promising results on open-domain and domain-specific downstream tasks. However, state-of-the-art Transformers require an unreasonably large amount of pre-training data and compute. In this paper, we propose FPDM (Fast Pre-training Technique using Document Level Metadata), a novel, compute-efficient framework that utilizes Document metadata and Domain-Specific Taxonomy as supervision signals to pre-train transformer encoder on a domain-specific corpus. The main innovation is that during domain-specific pretraining, an open-domain encoder is continually pre-trained using sentence-level embeddings as inputs (to accommodate long documents), however, fine-tuning is done with token-level embeddings as inputs to this encoder. We show that FPDM outperforms several transformer-based baselines in terms of character-level F1 scores and other automated metrics in the Customer Support, Scientific, and Legal Domains, and shows a negligible drop in performance on open-domain benchmarks. Importantly, the novel use of document-level supervision along with sentence-level embedding input for pre-training reduces pre-training compute by around 1,000, 4,500, and 500 times compared to MLM and/or NSP in Customer Support, Scientific, and Legal Domains, respectively. Code and datasets are available at https://bit.ly/FPDMCode.

Large pre-trained neural language models have brought immense progress to both NLP and software engineering. Models in OpenAI's GPT series now dwarf Google's BERT and Meta's RoBERTa, which previously set new benchmarks on a wide range of NLP applications. These models are trained on massive corpora of heterogeneous data from web crawls, which enables them to learn general language patterns and semantic relationships. However, the largest models are both expensive to train and deploy and are often closed-source, so we lack access to their data and design decisions. We argue that this trend towards large, general-purpose models should be complemented with single-purpose, more modestly sized pre-trained models. In this work, we take StackOverflow (SO) as a domain example in which large volumes of rich aligned code and text data is available. We adopt standard practices for pre-training large language models, including using a very large context size (2,048 tokens), batch size (0.5M tokens) and training set (27B tokens), coupled with a powerful toolkit (Megatron-LM), to train two models: SOBertBase, with 109M parameters, and SOBertLarge with 762M parameters, at a budget of just 187 and \800 each. We compare the performance of our models with both the previous SOTA model trained on SO data exclusively as well general-purpose BERT models and OpenAI's ChatGPT on four SO-specific downstream tasks - question quality prediction, closed question prediction, named entity recognition and obsoletion prediction (a new task we introduce). Not only do our models consistently outperform all baselines, the smaller model is often sufficient for strong results. Both models are released to the public. These results demonstrate that pre-training both extensively and properly on in-domain data can yield a powerful and affordable alternative to leveraging closed-source general-purpose models.

We present the zero-shot entity linking task, where mentions must be linked to unseen entities without in-domain labeled data. The goal is to enable robust transfer to highly specialized domains, and so no metadata or alias tables are assumed. In this setting, entities are only identified by text descriptions, and models must rely strictly on language understanding to resolve the new entities. First, we show that strong reading comprehension models pre-trained on large unlabeled data can be used to generalize to unseen entities. Second, we propose a simple and effective adaptive pre-training strategy, which we term domain-adaptive pre-training (DAP), to address the domain shift problem associated with linking unseen entities in a new domain. We present experiments on a new dataset that we construct for this task and show that DAP improves over strong pre-training baselines, including BERT. The data and code are available at https://github.com/lajanugen/zeshel.

Pretrained language models have served as important backbones for natural language processing. Recently, in-domain pretraining has been shown to benefit various domain-specific downstream tasks. In the biomedical domain, natural language generation (NLG) tasks are of critical importance, while understudied. Approaching natural language understanding (NLU) tasks as NLG achieves satisfying performance in the general domain through constrained language generation or language prompting. We emphasize the lack of in-domain generative language models and the unsystematic generative downstream benchmarks in the biomedical domain, hindering the development of the research community. In this work, we introduce the generative language model BioBART that adapts BART to the biomedical domain. We collate various biomedical language generation tasks including dialogue, summarization, entity linking, and named entity recognition. BioBART pretrained on PubMed abstracts has enhanced performance compared to BART and set strong baselines on several tasks. Furthermore, we conduct ablation studies on the pretraining tasks for BioBART and find that sentence permutation has negative effects on downstream tasks.

Many applications of machine learning require a model to make accurate pre-dictions on test examples that are distributionally different from training ones, while task-specific labels are scarce during training. An effective approach to this challenge is to pre-train a model on related tasks where data is abundant, and then fine-tune it on a downstream task of interest. While pre-training has been effective in many language and vision domains, it remains an open question how to effectively use pre-training on graph datasets. In this paper, we develop a new strategy and self-supervised methods for pre-training Graph Neural Networks (GNNs). The key to the success of our strategy is to pre-train an expressive GNN at the level of individual nodes as well as entire graphs so that the GNN can learn useful local and global representations simultaneously. We systematically study pre-training on multiple graph classification datasets. We find that naive strategies, which pre-train GNNs at the level of either entire graphs or individual nodes, give limited improvement and can even lead to negative transfer on many downstream tasks. In contrast, our strategy avoids negative transfer and improves generalization significantly across downstream tasks, leading up to 9.4% absolute improvements in ROC-AUC over non-pre-trained models and achieving state-of-the-art performance for molecular property prediction and protein function prediction.

Out-of-distribution (OOD) generalization is a favorable yet challenging property for deep neural networks. The core challenges lie in the limited availability of source domains that help models learn an invariant representation from the spurious features. Various domain augmentation have been proposed but largely rely on interpolating existing domains and frequently face difficulties in creating truly "novel" domains. Humans, on the other hand, can easily extrapolate novel domains, thus, an intriguing question arises: How can neural networks extrapolate like humans and achieve OOD generalization? We introduce a novel approach to domain extrapolation that leverages reasoning ability and the extensive knowledge encapsulated within large language models (LLMs) to synthesize entirely new domains. Starting with the class of interest, we query the LLMs to extract relevant knowledge for these novel domains. We then bridge the gap between the text-centric knowledge derived from LLMs and the pixel input space of the model using text-to-image generation techniques. By augmenting the training set of domain generalization datasets with high-fidelity, photo-realistic images of these new domains, we achieve significant improvements over all existing methods, as demonstrated in both single and multi-domain generalization across various benchmarks. With the ability to extrapolate any domains for any class, our method has the potential to learn a generalized model for any task without any data. To illustrate, we put forth a much more difficult setting termed, data-free domain generalization, that aims to learn a generalized model in the absence of any collected data. Our empirical findings support the above argument and our methods exhibit commendable performance in this setting, even surpassing the supervised setting by approximately 1-2\% on datasets such as VLCS.

Large language model pre-training has traditionally relied on human experts to craft heuristics for improving the corpora quality, resulting in numerous rules developed to date. However, these rules lack the flexibility to address the unique characteristics of individual example effectively. Meanwhile, applying tailored rules to every example is impractical for human experts. In this paper, we demonstrate that even small language models, with as few as 0.3B parameters, can exhibit substantial data refining capabilities comparable to those of human experts. We introduce Programming Every Example (ProX), a novel framework that treats data refinement as a programming task, enabling models to refine corpora by generating and executing fine-grained operations, such as string normalization, for each individual example at scale. Experimental results show that models pre-trained on ProX-curated data outperform either original data or data filtered by other selection methods by more than 2% across various downstream benchmarks. Its effectiveness spans various model sizes and pre-training corpora, including C4, RedPajama-V2, and FineWeb. Furthermore, ProX exhibits significant potential in domain-specific continual pre-training: without domain specific design, models trained on OpenWebMath refined by ProX outperform human-crafted rule-based methods, improving average accuracy by 7.6% over Mistral-7B, with 14.6% for Llama-2-7B and 20.3% for CodeLlama-7B, all within 10B tokens to be comparable to models like Llemma-7B trained on 200B tokens. Further analysis highlights that ProX significantly saves training FLOPs, offering a promising path for efficient LLM pre-training.We are open-sourcing ProX with >100B corpus, models, and sharing all training and implementation details for reproducible research and future innovation. Code: https://github.com/GAIR-NLP/ProX

Large Language Models (LLMs) have shown promise in highly-specialized domains, however challenges are still present in aspects of accuracy and costs. These limitations restrict the usage of existing models in domain-specific tasks. While fine-tuning pre-trained models have shown promising results, this process can be computationally expensive and require massive datasets of the specialized application in hand. In this work, we bridge that gap. We have developed Phi-2-Legal and Mistral-Legal-7B, which are language models specifically designed for legal applications. These models are based on Phi-2 and Mistral-7B-v0.1, and have gone through continued pre-training with over 500 million tokens of legal texts. Our innovative approach significantly improves capabilities in legal tasks by using Large Language Models (LLMs) to convert raw training data into reading comprehension text. Our legal LLMs have demonstrated superior performance in legal benchmarks, even outperforming models trained on much larger datasets with more resources. This work emphasizes the effectiveness of continued pre-training on domain-specific texts, while using affordable LLMs for data conversion, which gives these models domain expertise while retaining general language understanding capabilities. While this work uses the legal domain as a test case, our method can be scaled and applied to any pre-training dataset, resulting in significant improvements across different tasks. These findings underscore the potential of domain-adaptive pre-training and reading comprehension for the development of highly effective domain-specific language models.

Large language models (LLMs) are typically trained on general source data for various domains, but a recent surge in domain-specific LLMs has shown their potential to outperform general-purpose models in domain-specific tasks (e.g., biomedicine). Although domain-specific pre-training enhances efficiency and leads to smaller models, the computational costs of training these LLMs remain high, posing budgeting challenges. We introduce MediSwift, a suite of biomedical LMs that leverage sparse pre-training on domain-specific biomedical text data. By inducing up to 75% weight sparsity during the pre-training phase, MediSwift achieves a 2-2.5x reduction in training FLOPs. Notably, all sparse pre-training was performed on the Cerebras CS-2 system, which is specifically designed to realize the acceleration benefits from unstructured weight sparsity, thereby significantly enhancing the efficiency of the MediSwift models. Through subsequent dense fine-tuning and strategic soft prompting, MediSwift models outperform existing LLMs up to 7B parameters on biomedical tasks, setting new benchmarks w.r.t efficiency-accuracy on tasks such as PubMedQA. Our results show that sparse pre-training, along with dense fine-tuning and soft prompting, offers an effective method for creating high-performing, computationally efficient models in specialized domains.

Large language models (LLMs) have shown potential as tools for scientific discovery. This has engendered growing interest in their use in humanistic disciplines, such as historical linguistics and literary studies. These fields often construct arguments on the basis of delineations like genre, or more inflexibly, time period. Although efforts have been made to restrict inference to specific domains via fine-tuning or model editing, we posit that the only true guarantee is domain-restricted pretraining -- typically, a data- and compute-expensive proposition. We show that efficient pretraining techniques can produce useful models over corpora too large for easy manual inspection but too small for "typical" LLM approaches. We employ a novel date-attribution pipeline in order to obtain a temporally-segmented dataset of five 10-million-word slices. We train two corresponding five-model batteries over these corpus segments, efficient pretraining and Llama3-8B parameter efficiently finetuned. We find that the pretrained models are faster to train than the finetuned baselines and that they better respect the historical divisions of our corpus. Emphasizing speed and precision over a-historical comprehensiveness enables a number of novel approaches to hypothesis discovery and testing in our target fields. Taking up diachronic linguistics as a testbed, we show that our method enables the detection of a diverse set of phenomena, including en masse lexical change, non-lexical (grammatical and morphological) change, and word sense introduction/obsolescence. We provide a ready-to-use pipeline that allows extension of our approach to other target fields with only minimal adaptation.

The high computational cost associated with pretraining large language models limits their research. Two strategies have emerged to address this issue: domain specialization and pretraining with high-quality data. To explore these strategies, we specialized the Sabi\'a-2 Small model with 1.9 billion unique tokens from reputable Brazilian legal sources and conducted few-shot evaluations on legal and general knowledge exams. Our model, Juru, demonstrates the benefits of domain specialization with a reduced amount of pretraining data. However, this specialization comes at the expense of degrading performance in other knowledge areas within the same language. This study contributes to the growing body of scientific evidence showing that pretraining data selection may enhance the performance of large language models, enabling the exploration of these models at a lower cost.

Large Language Models (LLMs) have shown remarkable success in supporting a wide range of knowledge-intensive tasks. In specialized domains, there is growing interest in leveraging LLMs to assist subject matter experts with domain-specific challenges. However, deploying LLMs as SaaS solutions raises data privacy concerns, while many open-source models demand significant computational resources for effective domain adaptation and deployment. A promising alternative is to develop smaller, domain-specialized LLMs, though this approach is often constrained by the lack of high-quality domain-specific training data. In this work, we address these limitations by presenting a cost-efficient and scalable training pipeline that combines guided synthetic data generation from a small seed corpus with bottom-up domain data curation. Our pipeline integrates Domain-Adaptive Pretraining (DAPT), Domain-specific Supervised Fine-tuning (DSFT), and Direct Preference Optimization (DPO) to train effective small-scale models for specialized use cases. We demonstrate this approach through DiagnosticSLM, a 3B-parameter domain-specific model tailored for fault diagnosis, root cause analysis, and repair recommendation in industrial settings. To evaluate model performance, we introduce four domain-specific benchmarks: multiple-choice questions (DiagnosticMCQ), question answering (DiagnosticQA), sentence completion (DiagnosticComp), and summarization (DiagnosticSum). DiagnosticSLM achieves up to 25% accuracy improvement over open-source models of comparable or larger size (2B-9B) on the MCQ task, while also outperforming or matching them in other tasks, demonstrating effective domain-specific reasoning and generalization capabilities.

Pretraining directly on web-scale corpora is the de facto paradigm for building language models. We study an alternative setting where the model is initially exposed to abstract structured data, as a means to ease the subsequent acquisition of rich semantic knowledge, much like humans learn simple logic and mathematics before higher reasoning. We specifically focus on procedural data, generated by formal languages and other simple algorithms, as such abstract data. We first diagnose the algorithmic skills that different forms of procedural data can improve, often significantly. For example, on context recall (Needle-in-a-haystack), the accuracy jumps from 10 to 98% when pretraining on Dyck sequences (balanced brackets). Second, we study how these gains are reflected in pretraining larger models (up to 1.3B). We find that front-loading as little as 0.1% procedural data significantly outperforms standard pretraining on natural language, code, and informal mathematics (C4, CodeParrot, and DeepMind-Math datasets). Notably, this procedural pretraining enables the models to reach the same loss value with only 55, 67, 86% of the original data. Third, we explore the mechanisms behind and find that procedural pretraining instils non-trivial structure in both attention and MLP layers. The former is particularly important for structured domains (e.g. code), and the latter for language. Finally, we lay a path for combining multiple forms of procedural data. Our results show that procedural pretraining is a simple, lightweight means to improving performance and accelerating language model pretraining, ultimately suggesting the promise of disentangling knowledge acquisition from reasoning in LLMs.

Conventional continual pretraining (CPT) for large language model (LLM) domain adaptation often suffers from catastrophic forgetting and limited domain capacity. Existing strategies adopt layer expansion, introducing additional trainable parameters to accommodate new knowledge. However, the uniform expansion and updates still entangle general and domain learning, undermining its effectiveness. Our pilot studies reveal that LLMs exhibit functional specialization, where layers and units differentially encode general-critical capabilities, suggesting that parameter expansion and optimization should be function-aware. We then propose ADEPT, Adaptive Expansion and Dynamic Decoupled Tuning for continual pretraining, a two-stage framework for domain-adaptive CPT. ADEPT first performs General-Competence Guided Selective Layer Expansion, duplicating layers least critical for the general domain to increase representational capacity while minimizing interference with general knowledge. It then applies Adaptive Unit-Wise Decoupled Tuning, disentangling parameter units within expanded layers according to their general-domain importance and assigning asymmetric learning rates to balance knowledge injection and retention. Experiments on mathematical and medical benchmarks show that ADEPT outperforms full-parameter CPT by up to 5.76% on the general domain and 5.58% on the target domain with only 15% of parameters tuned and less than 50% training time. Ablation studies, theoretical analysis, and extended investigations further demonstrate the necessity of targeted expansion and decoupled optimization, providing new principles for efficient and robust domain-adaptive CPT. Our code is open-sourced at https://github.com/PuppyKnightUniversity/ADEPT

Large Language Models(LLMs) have shown exceptional abilities, yet training these models can be quite challenging. There is a strong dependence on the quality of data and finding the best instruction tuning set. Further, the inherent limitations in training methods create substantial difficulties to train relatively smaller models with 7B and 13B parameters. In our research, we suggest an improved training method for these models by utilising knowledge from larger models, such as a mixture of experts (8x7B) architectures. The scale of these larger models allows them to capture a wide range of variations from data alone, making them effective teachers for smaller models. Moreover, we implement a novel post-training domain alignment phase that employs domain-specific expert models to boost domain-specific knowledge during training while preserving the model's ability to generalise. Fine-tuning Mistral 7B and 2x7B with our method surpasses the performance of state-of-the-art language models with more than 7B and 13B parameters: achieving up to 7.9 in MT-Bench and 93.04% on AlpacaEval.

Pre-trained language models (PLMs) demonstrate excellent abilities to understand texts in the generic domain while struggling in a specific domain. Although continued pre-training on a large domain-specific corpus is effective, it is costly to tune all the parameters on the domain. In this paper, we investigate whether we can adapt PLMs both effectively and efficiently by only tuning a few parameters. Specifically, we decouple the feed-forward networks (FFNs) of the Transformer architecture into two parts: the original pre-trained FFNs to maintain the old-domain knowledge and our novel domain-specific adapters to inject domain-specific knowledge in parallel. Then we adopt a mixture-of-adapters gate to fuse the knowledge from different domain adapters dynamically. Our proposed Mixture-of-Domain-Adapters (MixDA) employs a two-stage adapter-tuning strategy that leverages both unlabeled data and labeled data to help the domain adaptation: i) domain-specific adapter on unlabeled data; followed by ii) the task-specific adapter on labeled data. MixDA can be seamlessly plugged into the pretraining-finetuning paradigm and our experiments demonstrate that MixDA achieves superior performance on in-domain tasks (GLUE), out-of-domain tasks (ChemProt, RCT, IMDB, Amazon), and knowledge-intensive tasks (KILT). Further analyses demonstrate the reliability, scalability, and efficiency of our method. The code is available at https://github.com/Amano-Aki/Mixture-of-Domain-Adapters.

Continual pre-training has been urgent for adapting a pre-trained model to a multitude of domains and tasks in the fast-evolving world. In practice, a continually pre-trained model is expected to demonstrate not only greater capacity when fine-tuned on pre-trained domains but also a non-decreasing performance on unseen ones. In this work, we first investigate such anytime fine-tuning effectiveness of existing continual pre-training approaches, concluding with unanimously decreased performance on unseen domains. To this end, we propose a prompt-guided continual pre-training method, where we train a hypernetwork to generate domain-specific prompts by both agreement and disagreement losses. The agreement loss maximally preserves the generalization of a pre-trained model to new domains, and the disagreement one guards the exclusiveness of the generated hidden states for each domain. Remarkably, prompts by the hypernetwork alleviate the domain identity when fine-tuning and promote knowledge transfer across domains. Our method achieved improvements of 3.57% and 3.4% on two real-world datasets (including domain shift and temporal shift), respectively, demonstrating its efficacy.

The pre-training and fine-tuning paradigm has contributed to a number of breakthroughs in Natural Language Processing (NLP). Instead of directly training on a downstream task, language models are first pre-trained on large datasets with cross-domain knowledge (e.g., Pile, MassiveText, etc.) and then fine-tuned on task-specific data (e.g., natural language generation, text summarization, etc.). Scaling the model and dataset size has helped improve the performance of LLMs, but unfortunately, this also lead to highly prohibitive computational costs. Pre-training LLMs often require orders of magnitude more FLOPs than fine-tuning and the model capacity often remains the same between the two phases. To achieve training efficiency w.r.t training FLOPs, we propose to decouple the model capacity between the two phases and introduce Sparse Pre-training and Dense Fine-tuning (SPDF). In this work, we show the benefits of using unstructured weight sparsity to train only a subset of weights during pre-training (Sparse Pre-training) and then recover the representational capacity by allowing the zeroed weights to learn (Dense Fine-tuning). We demonstrate that we can induce up to 75% sparsity into a 1.3B parameter GPT-3 XL model resulting in a 2.5x reduction in pre-training FLOPs, without a significant loss in accuracy on the downstream tasks relative to the dense baseline. By rigorously evaluating multiple downstream tasks, we also establish a relationship between sparsity, task complexity and dataset size. Our work presents a promising direction to train large GPT models at a fraction of the training FLOPs using weight sparsity, while retaining the benefits of pre-trained textual representations for downstream tasks.

In Self-Supervised Learning (SSL), models are typically pretrained, fine-tuned, and evaluated on the same domains. However, they tend to perform poorly when evaluated on unseen domains, a challenge that Unsupervised Domain Generalization (UDG) seeks to address. Current UDG methods rely on domain labels, which are often challenging to collect, and domain-specific architectures that lack scalability when confronted with numerous domains, making the current methodology impractical and rigid. Inspired by contrastive-based UDG methods that mitigate spurious correlations by restricting comparisons to examples from the same domain, we hypothesize that eliminating style variability within a batch could provide a more convenient and flexible way to reduce spurious correlations without requiring domain labels. To verify this hypothesis, we introduce Batch Styles Standardization (BSS), a relatively simple yet powerful Fourier-based method to standardize the style of images in a batch specifically designed for integration with SSL methods to tackle UDG. Combining BSS with existing SSL methods offers serious advantages over prior UDG methods: (1) It eliminates the need for domain labels or domain-specific network components to enhance domain-invariance in SSL representations, and (2) offers flexibility as BSS can be seamlessly integrated with diverse contrastive-based but also non-contrastive-based SSL methods. Experiments on several UDG datasets demonstrate that it significantly improves downstream task performances on unseen domains, often outperforming or rivaling with UDG methods. Finally, this work clarifies the underlying mechanisms contributing to BSS's effectiveness in improving domain-invariance in SSL representations and performances on unseen domain.

Recent advances in natural language processing (NLP) can be largely attributed to the advent of pre-trained language models such as BERT and RoBERTa. While these models demonstrate remarkable performance on general datasets, they can struggle in specialized domains such as medicine, where unique domain-specific terminologies, domain-specific abbreviations, and varying document structures are common. This paper explores strategies for adapting these models to domain-specific requirements, primarily through continuous pre-training on domain-specific data. We pre-trained several German medical language models on 2.4B tokens derived from translated public English medical data and 3B tokens of German clinical data. The resulting models were evaluated on various German downstream tasks, including named entity recognition (NER), multi-label classification, and extractive question answering. Our results suggest that models augmented by clinical and translation-based pre-training typically outperform general domain models in medical contexts. We conclude that continuous pre-training has demonstrated the ability to match or even exceed the performance of clinical models trained from scratch. Furthermore, pre-training on clinical data or leveraging translated texts have proven to be reliable methods for domain adaptation in medical NLP tasks.

Large Language Models (LLMs) perform well in general QA but often struggle in domain-specific scenarios. Retrieval-Augmented Generation (RAG) introduces external knowledge but suffers from hallucinations and latency due to noisy retrievals. Continued pretraining internalizes domain knowledge but is costly and lacks cross-domain flexibility. We attribute this challenge to the long-tail distribution of domain knowledge, which leaves partial yet useful internal knowledge underutilized. We further argue that knowledge acquisition should be progressive, mirroring human learning: first understanding concepts, then applying them to complex reasoning. To address this, we propose Selct2Know (S2K), a cost-effective framework that internalizes domain knowledge through an internal-external knowledge self-selection strategy and selective supervised fine-tuning. We also introduce a structured reasoning data generation pipeline and integrate GRPO to enhance reasoning ability. Experiments on medical, legal, and financial QA benchmarks show that S2K consistently outperforms existing methods and matches domain-pretrained LLMs with significantly lower cost.

Large Language Models (LLMs) have shown strong abilities in general language tasks, yet adapting them to specific domains remains a challenge. Current method like Domain Adaptive Pretraining (DAPT) requires costly full-parameter training and suffers from catastrophic forgetting. Meanwhile, Retrieval-Augmented Generation (RAG) introduces substantial inference latency due to expensive nearest-neighbor searches and longer context. This paper introduces Memory Decoder, a plug-and-play pretrained memory that enables efficient domain adaptation without changing the original model's parameters. Memory Decoder employs a small transformer decoder that learns to imitate the behavior of an external non-parametric retriever. Once trained, Memory Decoder can be seamlessly integrated with any pretrained language model that shares the same tokenizer, requiring no model-specific modifications. Experimental results demonstrate that Memory Decoder enables effective adaptation of various Qwen and Llama models to three distinct specialized domains: biomedicine, finance, and law, reducing perplexity by an average of 6.17 points. Overall, Memory Decoder introduces a novel paradigm centered on a specially pretrained memory component designed for domain-specific adaptation. This memory architecture can be integrated in a plug-and-play manner, consistently enhancing performance across multiple models within the target domain.

We introduce Domain-specific Masks for Generalization, a model for improving both in-domain and out-of-domain generalization performance. For domain generalization, the goal is to learn from a set of source domains to produce a single model that will best generalize to an unseen target domain. As such, many prior approaches focus on learning representations which persist across all source domains with the assumption that these domain agnostic representations will generalize well. However, often individual domains contain characteristics which are unique and when leveraged can significantly aid in-domain recognition performance. To produce a model which best generalizes to both seen and unseen domains, we propose learning domain specific masks. The masks are encouraged to learn a balance of domain-invariant and domain-specific features, thus enabling a model which can benefit from the predictive power of specialized features while retaining the universal applicability of domain-invariant features. We demonstrate competitive performance compared to naive baselines and state-of-the-art methods on both PACS and DomainNet.

Can a small amount of verified goal information steer the expensive self-supervised pretraining of foundation models? Standard pretraining optimizes a fixed proxy objective (e.g., next-token prediction), which can misallocate compute away from downstream capabilities of interest. We introduce V-Pretraining: a value-based, modality-agnostic method for controlled continued pretraining in which a lightweight task designer reshapes the pretraining task to maximize the value of each gradient step. For example, consider self-supervised learning (SSL) with sample augmentation. The V-Pretraining task designer selects pretraining tasks (e.g., augmentations) for which the pretraining loss gradient is aligned with a gradient computed over a downstream task (e.g., image segmentation). This helps steer pretraining towards relevant downstream capabilities. Notably, the pretrained model is never updated on downstream task labels; they are used only to shape the pretraining task. Under matched learner update budgets, V-Pretraining of 0.5B--7B language models improves reasoning (GSM8K test Pass@1) by up to 18% relative over standard next-token prediction using only 12% of GSM8K training examples as feedback. In vision SSL, we improve the state-of-the-art results on ADE20K by up to 1.07 mIoU and reduce NYUv2 RMSE while improving ImageNet linear accuracy, and we provide pilot evidence of improved token efficiency in continued pretraining.

This work presents a collection of multi-modal domain adapted large language models built upon the instruction tuned variants of open weight models (Gemma 3, Qwen 3, Gemma 4) using a relatively small dataset of around 50 million tokens. The dataset consists of open-access additive manufacturing journal articles with data extracted for the domain adaptive pretraining and visual instruction tuning processes. Various stages of the developed model are evaluated with the Additive-Manufacturing-Benchmark which consists of additive manufacturing domain specific tasks compiled published resources. Domain adapted and instruction tuned models exhibit proficiency in both language and vision based tasks, achieving accuracies upwards of 90% in general additive manufacturing knowledge. This domain adaptive pretraining and instruction tuning strategy outline an accessible specialization method for large language models to a domain such as additive manufacturing.

Continual pre-training on small-scale task-specific data is an effective method for improving large language models in new target fields, yet it risks catastrophic forgetting of their original capabilities. A common solution is to re-weight training data mixtures from source and target fields on a domain space to achieve balanced performance. Previous domain reweighting strategies rely on manual designation with certain heuristics based on human intuition or empirical results. In this work, we prove that more general heuristics can be parameterized by proposing Data Mixing Agent, the first model-based, end-to-end framework that learns to re-weight domains. The agent learns generalizable heuristics through reinforcement learning on large quantities of data mixing trajectories with corresponding feedback from an evaluation environment. Experiments in continual pre-training on math reasoning show that Data Mixing Agent outperforms strong baselines in achieving balanced performance across source and target field benchmarks. Furthermore, it generalizes well across unseen source fields, target models, and domain spaces without retraining. Direct application to the code generation field also indicates its adaptability across target domains. Further analysis showcases the agents' well-aligned heuristics with human intuitions and their efficiency in achieving superior model performance with less source-field data.

Pre-pretraining language models (LMs) on symbolic data can accelerate and improve natural language acquisition. However, existing pre-pretraining tasks, such as Dyck and procedural algorithms, rely on narrow primitives that fail to capture the expressive capacity of natural language. Moreover, prior studies remain restricted to relatively small token budgets, offering limited insight into skill emergence and representational dynamics. To address these limitations, we propose logic pre-pretraining (Logic-PPT) as a principled initialization strategy, leveraging formal derivations to impart richer structural and linguistic biases. Formal derivations require abstract mechanisms that are central to natural language, simultaneously binding variables, connecting quantifiers and relational dependencies, and composing predicate-argument structures over long contexts. Scaling our evaluation to a 100B-token regime, logic pre-pretraining substantially accelerates skill acquisition in LMs, achieving 80\% accuracy on linguistic tasks with 36B fewer tokens than standard initialization, and outperforming alternative pre-pretraining baselines. Mechanistically, formal derivations induce persistent structural reorganization, distinctively characterized by a lower-rank, spectrally concentrated representation space. Crucially, we show that this internal geometry enables improved model compressibility via pruning, matching the dense baseline performance even at approx33\% sparsity.

We introduce~Domain2Vec, a novel approach that decomposes any dataset into a linear combination of several meta-domains, a new concept designed to capture the key underlying features of datasets. Domain2Vec maintains a vocabulary of meta-domains and uses a classifier to decompose any given dataset into a domain vector that corresponds to a distribution over this vocabulary. These domain vectors enable the identification of the optimal data mixture for language model (LM) pretraining in a training-free manner under the \textbf{Distribution Alignment Assumption} (DA^{2}), which suggests that when the data distributions of the training set and the validation set are better aligned, a lower validation loss is achieved. Moreover, Domain2vec can be seamlessly integrated into previous works to model the relationship between domain vectors and LM performance, greatly enhancing the efficiency and scalability of previous methods. Extensive experiments demonstrate that Domain2Vec helps find the data mixture that enhances downstream task performance with minimal computational overhead. Specifically, Domain2Vec achieves the same validation loss on Pile-CC using only 51.5% of the computation required when training on the original mixture of The Pile dataset. Under equivalent compute budget, Domain2Vec improves downstream performance by an average of 2.83%.

Can one inject new concepts into an already trained generative model, while respecting its existing structure and knowledge? We propose a new task - domain expansion - to address this. Given a pretrained generator and novel (but related) domains, we expand the generator to jointly model all domains, old and new, harmoniously. First, we note the generator contains a meaningful, pretrained latent space. Is it possible to minimally perturb this hard-earned representation, while maximally representing the new domains? Interestingly, we find that the latent space offers unused, "dormant" directions, which do not affect the output. This provides an opportunity: By "repurposing" these directions, we can represent new domains without perturbing the original representation. In fact, we find that pretrained generators have the capacity to add several - even hundreds - of new domains! Using our expansion method, one "expanded" model can supersede numerous domain-specific models, without expanding the model size. Additionally, a single expanded generator natively supports smooth transitions between domains, as well as composition of domains. Code and project page available at https://yotamnitzan.github.io/domain-expansion/.

We study the pre-train + fine-tune strategy for data-to-text tasks. Our experiments indicate that text-to-text pre-training in the form of T5, enables simple, end-to-end transformer based models to outperform pipelined neural architectures tailored for data-to-text generation, as well as alternative language model based pre-training techniques such as BERT and GPT-2. Importantly, T5 pre-training leads to better generalization, as evidenced by large improvements on out-of-domain test sets. We hope our work serves as a useful baseline for future research, as transfer learning becomes ever more prevalent for data-to-text tasks.

Due to privacy, storage, and other constraints, there is a growing need for unsupervised domain adaptation techniques in machine learning that do not require access to the data used to train a collection of source models. Existing methods for multi-source-free domain adaptation (MSFDA) typically train a target model using pseudo-labeled data produced by the source models, which focus on improving the pseudo-labeling techniques or proposing new training objectives. Instead, we aim to analyze the fundamental limits of MSFDA. In particular, we develop an information-theoretic bound on the generalization error of the resulting target model, which illustrates an inherent bias-variance trade-off. We then provide insights on how to balance this trade-off from three perspectives, including domain aggregation, selective pseudo-labeling, and joint feature alignment, which leads to the design of novel algorithms. Experiments on multiple datasets validate our theoretical analysis and demonstrate the state-of-art performance of the proposed algorithm, especially on some of the most challenging datasets, including Office-Home and DomainNet.

While Large Language Models (LLMs) demonstrate exceptional natural language capabilities, general-purpose models lack specialized domain knowledge for effective cybersecurity analysis. In this work, we investigate Domain-Adaptive Continuous Pretraining (DAP) as a methodology for enhancing cybersecurity understanding in pretrained LLMs while preserving general language capabilities. We systematically adapted three decoder-based architectures -- Llama-3.1-8B, DeepSeek-R1-Distill-Qwen-14B, and Llama-3.3-70B-Instruct -- using a curated 126-million-word cybersecurity corpus from standards, academic literature, and various other sources. Our approach employed constrained training parameters and distributed FSDP training to balance domain specialization with knowledge preservation. Evaluation across three cybersecurity benchmarks, namely, CTI-MCQ, CyberMetric, and SecEval, demonstrates consistent improvements post-adaptation. The Llama-3.3-70B-Ins-DAP model achieved state-of-the-art accuracies of 0.718, 0.933, and 0.864, respectively, outperforming specialized models, including Llama-Primus-Base. Notably, competitive performance was achieved using substantially smaller datasets (118.8 million versus 2.77 billion tokens), demonstrating efficient domain specialization viability. We establish that targeted continuous pretraining enables effective cybersecurity domain adaptation with computational feasibility, providing foundations for specialized AI assistants in threat analysis, vulnerability assessment, and security documentation while challenging prevailing assumptions about data requirements for LLM specialization.

Pretraining on large-scale, unstructured internet text has enabled language models to acquire a significant amount of world knowledge. However, this knowledge acquisition is data-inefficient -- to learn a given fact, models must be trained on hundreds to thousands of diverse representations of it. This poses a challenge when adapting a pretrained model to a small corpus of domain-specific documents, where each fact may appear rarely or only once. We propose to bridge this gap with synthetic continued pretraining: using the small domain-specific corpus to synthesize a large corpus more amenable to learning, and then performing continued pretraining on the synthesized corpus. We instantiate this proposal with EntiGraph, a synthetic data augmentation algorithm that extracts salient entities from the source documents and then generates diverse text by drawing connections between the sampled entities. Synthetic continued pretraining using EntiGraph enables a language model to answer questions and follow generic instructions related to the source documents without access to them. If instead, the source documents are available at inference time, we show that the knowledge acquired through our approach compounds with retrieval-augmented generation. To better understand these results, we build a simple mathematical model of EntiGraph, and show how synthetic data augmentation can "rearrange" knowledge to enable more data-efficient learning.

Continual Pre-Training (CPT) on Large Language Models (LLMs) has been widely used to expand the model's fundamental understanding of specific downstream domains (e.g., math and code). For the CPT on domain-specific LLMs, one important question is how to choose the optimal mixture ratio between the general-corpus (e.g., Dolma, Slim-pajama) and the downstream domain-corpus. Existing methods usually adopt laborious human efforts by grid-searching on a set of mixture ratios, which require high GPU training consumption costs. Besides, we cannot guarantee the selected ratio is optimal for the specific domain. To address the limitations of existing methods, inspired by the Scaling Law for performance prediction, we propose to investigate the Scaling Law of the Domain-specific Continual Pre-Training (D-CPT Law) to decide the optimal mixture ratio with acceptable training costs for LLMs of different sizes. Specifically, by fitting the D-CPT Law, we can easily predict the general and downstream performance of arbitrary mixture ratios, model sizes, and dataset sizes using small-scale training costs on limited experiments. Moreover, we also extend our standard D-CPT Law on cross-domain settings and propose the Cross-Domain D-CPT Law to predict the D-CPT law of target domains, where very small training costs (about 1% of the normal training costs) are needed for the target domains. Comprehensive experimental results on six downstream domains demonstrate the effectiveness and generalizability of our proposed D-CPT Law and Cross-Domain D-CPT Law.

Pre-trained Vision-Language Models (VLMs) exhibit strong generalization capabilities, enabling them to recognize a wide range of objects across diverse domains without additional training. However, they often retain irrelevant information beyond the requirements of specific downstream tasks, raising concerns about computational efficiency and potential information leakage. This has motivated growing interest in approximate unlearning, which aims to selectively remove unnecessary knowledge while preserving overall model performance. Existing approaches to approximate unlearning have primarily focused on class unlearning, where a VLM is retrained to fail to recognize specified object classes while maintaining accuracy for others. However, merely forgetting object classes is often insufficient in practical applications. For instance, an autonomous driving system should accurately recognize real cars while avoiding misrecognition of illustrated cars depicted in roadside advertisements as real cars, which could be hazardous. In this paper, we introduce Approximate Domain Unlearning (ADU), a novel problem setting that requires reducing recognition accuracy for images from specified domains (e.g., illustration) while preserving accuracy for other domains (e.g., real). ADU presents new technical challenges: due to the strong domain generalization capability of pre-trained VLMs, domain distributions are highly entangled in the feature space, making naive approaches based on penalizing target domains ineffective. To tackle this limitation, we propose a novel approach that explicitly disentangles domain distributions and adaptively captures instance-specific domain information. Extensive experiments show that our approach outperforms baselines built upon VLM tuning techniques, paving the way for practical and fine-grained unlearning in VLMs. Code: https://kodaikawamura.github.io/Domain_Unlearning/.

Distribution shift presents a significant challenge in machine learning, where models often underperform during the test stage when faced with a different distribution than the one they were trained on. This paper focuses on domain shifts, which occur when the model is applied to new domains that are different from the ones it was trained on, and propose a new approach called D^3G. Unlike previous methods that aim to learn a single model that is domain invariant, D^3G leverages domain similarities based on domain metadata to learn domain-specific models. Concretely, D^3G learns a set of training-domain-specific functions during the training stage and reweights them based on domain relations during the test stage. These domain relations can be directly obtained and learned from domain metadata. Under mild assumptions, we theoretically prove that using domain relations to reweight training-domain-specific functions achieves stronger out-of-domain generalization compared to the conventional averaging approach. Empirically, we evaluate the effectiveness of D^3G using real-world datasets for tasks such as temperature regression, land use classification, and molecule-protein binding affinity prediction. Our results show that D^3G consistently outperforms state-of-the-art methods.

Existing pretraining data mixing methods for large language models (LLMs) typically follow a domain-wise methodology, a top-down process that first determines domain weights and then performs uniform data sampling across each domain. However, these approaches neglect significant inter-domain overlaps and commonalities, failing to control the global diversity of the constructed training dataset. Further, uniform sampling within domains ignores fine-grained sample-specific features, potentially leading to suboptimal data distribution. To address these shortcomings, we propose a novel sample-wise data mixture approach based on a bottom-up paradigm. This method performs global cross-domain sampling by systematically evaluating the quality and diversity of each sample, thereby dynamically determining the optimal domain distribution. Comprehensive experiments across multiple downstream tasks and perplexity assessments demonstrate that SampleMix surpasses existing domain-based methods. Meanwhile, SampleMix requires 1.4x to 2.1x training steps to achieves the baselines' performance, highlighting the substantial potential of SampleMix to optimize pre-training data.

Cross-domain named entity recognition (NER) models are able to cope with the scarcity issue of NER samples in target domains. However, most of the existing NER benchmarks lack domain-specialized entity types or do not focus on a certain domain, leading to a less effective cross-domain evaluation. To address these obstacles, we introduce a cross-domain NER dataset (CrossNER), a fully-labeled collection of NER data spanning over five diverse domains with specialized entity categories for different domains. Additionally, we also provide a domain-related corpus since using it to continue pre-training language models (domain-adaptive pre-training) is effective for the domain adaptation. We then conduct comprehensive experiments to explore the effectiveness of leveraging different levels of the domain corpus and pre-training strategies to do domain-adaptive pre-training for the cross-domain task. Results show that focusing on the fractional corpus containing domain-specialized entities and utilizing a more challenging pre-training strategy in domain-adaptive pre-training are beneficial for the NER domain adaptation, and our proposed method can consistently outperform existing cross-domain NER baselines. Nevertheless, experiments also illustrate the challenge of this cross-domain NER task. We hope that our dataset and baselines will catalyze research in the NER domain adaptation area. The code and data are available at https://github.com/zliucr/CrossNER.

The paradigm of large-scale pre-training followed by downstream fine-tuning has been widely employed in various object detection algorithms. In this paper, we reveal discrepancies in data, model, and task between the pre-training and fine-tuning procedure in existing practices, which implicitly limit the detector's performance, generalization ability, and convergence speed. To this end, we propose AlignDet, a unified pre-training framework that can be adapted to various existing detectors to alleviate the discrepancies. AlignDet decouples the pre-training process into two stages, i.e., image-domain and box-domain pre-training. The image-domain pre-training optimizes the detection backbone to capture holistic visual abstraction, and box-domain pre-training learns instance-level semantics and task-aware concepts to initialize the parts out of the backbone. By incorporating the self-supervised pre-trained backbones, we can pre-train all modules for various detectors in an unsupervised paradigm. As depicted in Figure 1, extensive experiments demonstrate that AlignDet can achieve significant improvements across diverse protocols, such as detection algorithm, model backbone, data setting, and training schedule. For example, AlignDet improves FCOS by 5.3 mAP, RetinaNet by 2.1 mAP, Faster R-CNN by 3.3 mAP, and DETR by 2.3 mAP under fewer epochs.

This work focuses on leveraging and selecting from vast, unlabeled, open data to pre-fine-tune a pre-trained language model. The goal is to minimize the need for costly domain-specific data for subsequent fine-tuning while achieving desired performance levels. While many data selection algorithms have been designed for small-scale applications, rendering them unsuitable for our context, some emerging methods do cater to language data scales. However, they often prioritize data that aligns with the target distribution. While this strategy may be effective when training a model from scratch, it can yield limited results when the model has already been pre-trained on a different distribution. Differing from prior work, our key idea is to select data that nudges the pre-training distribution closer to the target distribution. We show the optimality of this approach for fine-tuning tasks under certain conditions. We demonstrate the efficacy of our methodology across a diverse array of tasks (NLU, NLG, zero-shot) with models up to 2.7B, showing that it consistently surpasses other selection methods. Moreover, our proposed method is significantly faster than existing techniques, scaling to millions of samples within a single GPU hour. Our code is open-sourced (Code repository: https://anonymous.4open.science/r/DV4LLM-D761/ ). While fine-tuning offers significant potential for enhancing performance across diverse tasks, its associated costs often limit its widespread adoption; with this work, we hope to lay the groundwork for cost-effective fine-tuning, making its benefits more accessible.

Large language models (LLMs) demonstrate strong code generation abilities in general-purpose programming languages but remain limited in specialized domains such as low-level embedded systems programming. This domain involves hardware register manipulation, vendor-specific SDKs, real-time operating system APIs, and hardware abstraction layers that are underrepresented in standard pretraining corpora. We introduce H2LooP Spark Preview, a continual pretraining (CPT) pipeline that adapts the OLMo-3-7B-a fully open language model to the embedded systems domain using BF16 LoRA with rank-stabilized scaling on 8 NVIDIA H100 GPUs. Our training corpus is constructed from repository-datasheet pairs covering 100B tokens of raw embedded systems data across 117 manufacturers, processed using the hierarchical datasheet-to-code mapping approach proposed in SpecMap (Nipane et al., 2026). The resulting curated dataset split contains 23.5B tokens across 13 embedded domains. Continual pretraining with high-rank LoRA (r=512) yields substantial gains, reducing in-domain perplexity by 70.4% and held-out repository perplexity by 66.1%. On generative code completion benchmarks spanning 13 embedded domains, our 7B model outperforms Claude Opus 4.6 and Qwen3-Coder-30B on 8 categories in token accuracy, showing that targeted continual pretraining enables smaller open-weight models to rival frontier systems on specialized technical tasks. We release the production training checkpoint on Huggingface as an open-source artifact.

Domain adaptation (DA) aims to transfer knowledge from a fully labeled source to a scarcely labeled or totally unlabeled target under domain shift. Recently, semi-supervised learning-based (SSL) techniques that leverage pseudo labeling have been increasingly used in DA. Despite the competitive performance, these pseudo labeling methods rely heavily on the source domain to generate pseudo labels for the target domain and therefore still suffer considerably from source data bias. Moreover, class distribution bias in the target domain is also often ignored in the pseudo label generation and thus leading to further deterioration of performance. In this paper, we propose GeT that learns a non-bias target embedding distribution with high quality pseudo labels. Specifically, we formulate an online target generative classifier to induce the target distribution into distinctive Gaussian components weighted by their class priors to mitigate source data bias and enhance target class discriminability. We further propose a structure similarity regularization framework to alleviate target class distribution bias and further improve target class discriminability. Experimental results show that our proposed GeT is effective and achieves consistent improvements under various DA settings with and without class distribution bias. Our code is available at: https://lulusindazc.github.io/getproject/.

We study extractive question-answering in the medical domain (Medical-EQA). This problem has two main challenges: (i) domain specificity, as most AI models lack necessary domain knowledge, and (ii) extraction-based answering style, which restricts most autoregressive LLMs due to potential hallucinations. To handle those challenges, we propose TOP-Training, a target-oriented pre-training paradigm that stands out among all domain adaptation techniques with two desirable features: (i) TOP-Training moves one step further than popular domain-oriented fine-tuning since it not only moves closer to the target domain, but also familiarizes itself with the target dataset, and (ii) it does not assume the existence of a large set of unlabeled instances from the target domain. Specifically, for a target Medical-EQA dataset, we extract its entities and leverage large language models (LLMs) to generate synthetic texts containing those entities; we then demonstrate that pretraining on this synthetic text data yields better performance on the target Medical-EQA benchmarks. Overall, our contributions are threefold: (i) TOP-Training, a new pretraining technique to effectively adapt LLMs to better solve a target problem, (ii) TOP-Training has a wide application scope because it does not require the target problem to have a large set of unlabeled data, and (iii) our experiments highlight the limitations of autoregressive LLMs, emphasizing TOP-Training as a means to unlock the true potential of bidirectional LLMs.

The goal of domain generalization algorithms is to predict well on distributions different from those seen during training. While a myriad of domain generalization algorithms exist, inconsistencies in experimental conditions -- datasets, architectures, and model selection criteria -- render fair and realistic comparisons difficult. In this paper, we are interested in understanding how useful domain generalization algorithms are in realistic settings. As a first step, we realize that model selection is non-trivial for domain generalization tasks. Contrary to prior work, we argue that domain generalization algorithms without a model selection strategy should be regarded as incomplete. Next, we implement DomainBed, a testbed for domain generalization including seven multi-domain datasets, nine baseline algorithms, and three model selection criteria. We conduct extensive experiments using DomainBed and find that, when carefully implemented, empirical risk minimization shows state-of-the-art performance across all datasets. Looking forward, we hope that the release of DomainBed, along with contributions from fellow researchers, will streamline reproducible and rigorous research in domain generalization.

Domain generalization (DG) aims to learn a robust model from source domains that generalize well on unseen target domains. Recent studies focus on generating novel domain samples or features to diversify distributions complementary to source domains. Yet, these approaches can hardly deal with the restriction that the samples synthesized from various domains can cause semantic distortion. In this paper, we propose an online one-stage Cross Contrasting Feature Perturbation (CCFP) framework to simulate domain shift by generating perturbed features in the latent space while regularizing the model prediction against domain shift. Different from the previous fixed synthesizing strategy, we design modules with learnable feature perturbations and semantic consistency constraints. In contrast to prior work, our method does not use any generative-based models or domain labels. We conduct extensive experiments on a standard DomainBed benchmark with a strict evaluation protocol for a fair comparison. Comprehensive experiments show that our method outperforms the previous state-of-the-art, and quantitative analyses illustrate that our approach can alleviate the domain shift problem in out-of-distribution (OOD) scenarios.

Recent work has demonstrated that pre-training in-domain language models can boost performance when adapting to a new domain. However, the costs associated with pre-training raise an important question: given a fixed budget, what steps should an NLP practitioner take to maximize performance? In this paper, we view domain adaptation with a constrained budget as a consumer choice problem, where the goal is to select an optimal combination of data annotation and pre-training. We measure annotation costs of three procedural text datasets, along with the pre-training costs of several in-domain language models. The utility of different combinations of pre-training and data annotation are evaluated under varying budget constraints to assess which combination strategy works best. We find that for small budgets, spending all funds on annotation leads to the best performance; once the budget becomes large enough, however, a combination of data annotation and in-domain pre-training yields better performance. Our experiments suggest task-specific data annotation should be part of an economical strategy when adapting an NLP model to a new domain.

We present results from a large-scale experiment on pretraining encoders with non-embedding parameter counts ranging from 700M to 9.3B, their subsequent distillation into smaller models ranging from 17M-170M parameters, and their application to the Natural Language Understanding (NLU) component of a virtual assistant system. Though we train using 70% spoken-form data, our teacher models perform comparably to XLM-R and mT5 when evaluated on the written-form Cross-lingual Natural Language Inference (XNLI) corpus. We perform a second stage of pretraining on our teacher models using in-domain data from our system, improving error rates by 3.86% relative for intent classification and 7.01% relative for slot filling. We find that even a 170M-parameter model distilled from our Stage 2 teacher model has 2.88% better intent classification and 7.69% better slot filling error rates when compared to the 2.3B-parameter teacher trained only on public data (Stage 1), emphasizing the importance of in-domain data for pretraining. When evaluated offline using labeled NLU data, our 17M-parameter Stage 2 distilled model outperforms both XLM-R Base (85M params) and DistillBERT (42M params) by 4.23% to 6.14%, respectively. Finally, we present results from a full virtual assistant experimentation platform, where we find that models trained using our pretraining and distillation pipeline outperform models distilled from 85M-parameter teachers by 3.74%-4.91% on an automatic measurement of full-system user dissatisfaction.

Large language models exhibit promising general capabilities but often lack specialized knowledge for domain-specific tasks. Developing domain experts from a base model enables a range of applications without prohibitive training costs. This work demonstrates a method using continuous training and instruction fine-tuning to rapidly adapt Llama 2 base models to the Chinese medical domain. We first conduct continuous training on 1B tokens from Chinese medical references to teach relevant vocabulary and knowledge. The models are then fine-tuned on 54K examples sourced from the Chinese National Medical Licensing Examination. Experiments on Chinese medical data confirm the effectiveness of this approach, producing a model comparable to GPT-3.5-turbo while using way less computational resource. The resulting domain-specific model could be useful for various Chinese medical applications. More broadly, this provides a template for domain-specific training of large language models in areas where pre-trained models lack the required expertise, such as law, science, and engineering.

Machine learning systems typically assume that the distributions of training and test sets match closely. However, a critical requirement of such systems in the real world is their ability to generalize to unseen domains. Here, we propose an inter-domain gradient matching objective that targets domain generalization by maximizing the inner product between gradients from different domains. Since direct optimization of the gradient inner product can be computationally prohibitive -- requires computation of second-order derivatives -- we derive a simpler first-order algorithm named Fish that approximates its optimization. We demonstrate the efficacy of Fish on 6 datasets from the Wilds benchmark, which captures distribution shift across a diverse range of modalities. Our method produces competitive results on these datasets and surpasses all baselines on 4 of them. We perform experiments on both the Wilds benchmark, which captures distribution shift in the real world, as well as datasets in DomainBed benchmark that focuses more on synthetic-to-real transfer. Our method produces competitive results on both benchmarks, demonstrating its effectiveness across a wide range of domain generalization tasks.

Language models (LMs) have been instrumental for the rapid advance of natural language processing. This paper studies continual pre-training of LMs, in particular, continual domain-adaptive pre-training (or continual DAP-training). Existing research has shown that further pre-training an LM using a domain corpus to adapt the LM to the domain can improve the end-task performance in the domain. This paper proposes a novel method to continually DAP-train an LM with a sequence of unlabeled domain corpora to adapt the LM to these domains to improve their end-task performances. The key novelty of our method is a soft-masking mechanism that directly controls the update to the LM. A novel proxy is also proposed to preserve the general knowledge in the original LM. Additionally, it contrasts the representations of the previously learned domain knowledge (including the general knowledge in the pre-trained LM) and the knowledge from the current full network to achieve knowledge integration. The method not only overcomes catastrophic forgetting, but also achieves knowledge transfer to improve end-task performances. Empirical evaluation demonstrates the effectiveness of the proposed method.

Domain Generation Algorithms (DGAs) evolve continuously to evade botnet detection, posing a persistent challenge for dependable network defense. While deep learning-based detectors achieve strong performance under static conditions, they suffer severe degradation when facing temporal drift. Through a 9-year longitudinal study (2017-2025), we empirically show that state-of-the-art character- and word-based DGA classifiers rapidly lose effectiveness as new DGA variants emerge. To address this problem, we propose a drift-resilient Transformer-based framework that learns invariant representations through a hybrid tokenization strategy and multi-task self-supervised pre-training. The model integrates (i) character-level encoding to capture stochastic morphological patterns and (ii) subword-level encoding for word-based DGAs. Three pre-training tasks enable the model to learn robust structural and contextual features prior to supervised fine-tuning. Comprehensive evaluations demonstrate that our method significantly mitigates temporal degradation and consistently outperforms state-of-the-art baselines in forward-chaining experiments. The proposed approach offers a dependable foundation for long-term DGA defense in evolving threat landscapes. Our code is available at: https://github.com/snsec-net/2026-DSN-DRIFT.

Existing pre-trained models are generally geared towards a particular class of problems. To date, there seems to be still no consensus on what the right architecture and pre-training setup should be. This paper presents a unified framework for pre-training models that are universally effective across datasets and setups. We begin by disentangling architectural archetypes with pre-training objectives -- two concepts that are commonly conflated. Next, we present a generalized & unified perspective for self-supervision in NLP and show how different pre-training objectives can be cast as one another and how interpolating between different objectives can be effective. We then propose Mixture-of-Denoisers (MoD), a pre-training objective that combines diverse pre-training paradigms together. We furthermore introduce a notion of mode switching, wherein downstream fine-tuning is associated with specific pre-training schemes. We conduct extensive ablative experiments to compare multiple pre-training objectives and find that our method pushes the Pareto-frontier by outperforming T5 & GPT-like models across multiple diverse setups. By scaling our model up to 20B parameters, we achieve SOTA performance on 50 well-established supervised finetuning based NLP tasks. Our model also achieve strong results at in-context learning, outperforming 175B GPT-3 on zero-shot SuperGLUE and tripling the performance of T5-XXL on one-shot summarization. On 0-shot MMLU, UL2 20B outperforms T0 and T5 models. UL2 20B also works well with chain-of-thought prompting and reasoning, making it an appealing choice for research into reasoning at a small to medium scale of 20B parameters. Finally, we apply FLAN instruction tuning to the UL2 20B model, achieving MMLU and Big-Bench scores competitive to FLAN-PaLM 62B. We release Flax-based T5X checkpoints for the UL2 20B & Flan-UL2 20B.

Large Language Models (LLMs) remain substantially less data-efficient than humans. Pre-pretraining (PPT) on synthetic languages has been proposed to close this gap, with prior work emphasizing highly expressive formal languages such as k-Shuffle Dyck. Inspired by the Language Acquisition Device (LAD) hypothesis, which posits that innate constraints preemptively restrict the learner's hypothesis space to natural-language-like structure, we propose LAD-inspired PPT: pre-pretraining on MP-STRUCT, a formal language whose strings encode hierarchical composition, feature-based dependencies, and long-distance displacement via MERGE, AGREE, and MOVE. A brief 500-step PPT with MP-STRUCT matches strong formal-language baselines in token efficiency while additionally imparting a human-like resistance to structurally implausible languages (e.g., REVERSE). Analyzing simplified variants, we find that MP-STRUCT CORE outperforms k-Shuffle Dyck despite not being definable in C-RASP (a formal bound on transformer expressivity), challenging the prior hypothesis that effective PPT languages must be both hierarchically expressive and circuit-theoretically learnable. We show that functional landmarks, which reduce dependency resolution ambiguity, are a key driver, suggesting that effective PPT design depends not only on expressivity but also on the accessibility of dependency resolution.

Large Language Models (LLMs) excel in diverse tasks but often underperform in specialized fields due to limited domain-specific or proprietary corpus. Continual pre-training (CPT) enhances LLM capabilities by imbuing new domain-specific or proprietary knowledge while replaying general corpus to prevent catastrophic forgetting. The data mixture ratio of general corpus and domain-specific corpus, however, has been chosen heuristically, leading to sub-optimal training efficiency in practice. In this context, we attempt to re-visit the scaling behavior of LLMs under the hood of CPT, and discover a power-law relationship between loss, mixture ratio, and training tokens scale. We formalize the trade-off between general and domain-specific capabilities, leading to a well-defined Critical Mixture Ratio (CMR) of general and domain data. By striking the balance, CMR maintains the model's general ability and achieves the desired domain transfer, ensuring the highest utilization of available resources. Considering the balance between efficiency and effectiveness, CMR can be regarded as the optimal mixture ratio. Through extensive experiments, we ascertain the predictability of CMR, propose CMR scaling law and have substantiated its generalization. These findings offer practical guidelines for optimizing LLM training in specialized domains, ensuring both general and domain-specific performance while efficiently managing training resources.

Large Language Models (LLMs) have demonstrated remarkable proficiency in understanding and generating natural language. However, their capabilities wane in highly specialized domains underrepresented in the pretraining corpus, such as physical and biomedical sciences. This work explores how to repurpose general LLMs into effective task solvers for specialized domains. We introduce a novel, model-agnostic framework for learning custom input tags, which are parameterized as continuous vectors appended to the LLM's embedding layer, to condition the LLM. We design two types of input tags: domain tags are used to delimit specialized representations (e.g., chemical formulas) and provide domain-relevant context; function tags are used to represent specific functions (e.g., predicting molecular properties) and compress function-solving instructions. We develop a three-stage protocol to learn these tags using auxiliary data and domain knowledge. By explicitly disentangling task domains from task functions, our method enables zero-shot generalization to unseen problems through diverse combinations of the input tags. It also boosts LLM's performance in various specialized domains, such as predicting protein or chemical properties and modeling drug-target interactions, outperforming expert models tailored to these tasks.

Domain generalization (DG) aims to avoid the performance degradation of the model when the distribution shift between the limited training data and unseen test data occurs. Recently, foundation models with enormous parameters have been pre-trained with huge datasets, demonstrating strong generalization ability and showing promising direction for solving the DG problem. However, fully Fine-Tuning (FT) the foundation models results in unsatisfactory out-of-distribution accuracy due to the destroyed pre-trained generalized features. Recently, Parameter-Efficient Fine-Tuning (PEFT) alleviates the above problem by fine-tuning a small portion of the model parameters while keeping the rest frozen, which achieves better generalization performance compared to FT. Nevertheless, PEFT still suffers from the issue of overfitting to the training domains. To address the above issue, we propose Parameter-Efficient Group with Orthogonal regularization (PEGO) for vision transformers, which effectively preserves the generalization ability of the pre-trained network and learns more diverse knowledge compared with conventional PEFT. Specifically, we inject a group of trainable Low-Rank Adaptation (LoRA) modules into the pre-trained model and propose an orthogonal regularization loss to enhance the generalization ability of the model. Our framework achieves SOTA performance on five DG benchmarks, while only requiring training a small number of parameters without adding additional testing cost.

Face anti-spoofing (FAS) based on domain generalization (DG) has been recently studied to improve the generalization on unseen scenarios. Previous methods typically rely on domain labels to align the distribution of each domain for learning domain-invariant representations. However, artificial domain labels are coarse-grained and subjective, which cannot reflect real domain distributions accurately. Besides, such domain-aware methods focus on domain-level alignment, which is not fine-grained enough to ensure that learned representations are insensitive to domain styles. To address these issues, we propose a novel perspective for DG FAS that aligns features on the instance level without the need for domain labels. Specifically, Instance-Aware Domain Generalization framework is proposed to learn the generalizable feature by weakening the features' sensitivity to instance-specific styles. Concretely, we propose Asymmetric Instance Adaptive Whitening to adaptively eliminate the style-sensitive feature correlation, boosting the generalization. Moreover, Dynamic Kernel Generator and Categorical Style Assembly are proposed to first extract the instance-specific features and then generate the style-diversified features with large style shifts, respectively, further facilitating the learning of style-insensitive features. Extensive experiments and analysis demonstrate the superiority of our method over state-of-the-art competitors. Code will be publicly available at https://github.com/qianyuzqy/IADG.

Large Language Models (LLMs) like ChatGPT and GPT-4 are versatile and capable of addressing a diverse range of tasks. However, general LLMs, which are developed on open-domain data, may lack the domain-specific knowledge essential for tasks in vertical domains, such as legal, medical, etc. To address this issue, previous approaches either conduct continuous pre-training with domain-specific data or employ retrieval augmentation to support general LLMs. Unfortunately, these strategies are either cost-intensive or unreliable in practical applications. To this end, we present a novel framework named BLADE, which enhances Black-box LArge language models with small Domain-spEcific models. BLADE consists of a black-box LLM and a small domain-specific LM. The small LM preserves domain-specific knowledge and offers specialized insights, while the general LLM contributes robust language comprehension and reasoning capabilities. Specifically, our method involves three steps: 1) pre-training the small LM with domain-specific data, 2) fine-tuning this model using knowledge instruction data, and 3) joint Bayesian optimization of the general LLM and the small LM. Extensive experiments conducted on public legal and medical benchmarks reveal that BLADE significantly outperforms existing approaches. This shows the potential of BLADE as an effective and cost-efficient solution in adapting general LLMs for vertical domains.

Unsupervised domain translation (UDT) aims to find functions that convert samples from one domain (e.g., sketches) to another domain (e.g., photos) without changing the high-level semantic meaning (also referred to as ``content''). The translation functions are often sought by probability distribution matching of the transformed source domain and target domain. CycleGAN stands as arguably the most representative approach among this line of work. However, it was noticed in the literature that CycleGAN and variants could fail to identify the desired translation functions and produce content-misaligned translations. This limitation arises due to the presence of multiple translation functions -- referred to as ``measure-preserving automorphism" (MPA) -- in the solution space of the learning criteria. Despite awareness of such identifiability issues, solutions have remained elusive. This study delves into the core identifiability inquiry and introduces an MPA elimination theory. Our analysis shows that MPA is unlikely to exist, if multiple pairs of diverse cross-domain conditional distributions are matched by the learning function. Our theory leads to a UDT learner using distribution matching over auxiliary variable-induced subsets of the domains -- other than over the entire data domains as in the classical approaches. The proposed framework is the first to rigorously establish translation identifiability under reasonable UDT settings, to our best knowledge. Experiments corroborate with our theoretical claims.

The objective of domain generalization (DG) is to enhance the transferability of the model learned from a source domain to unobserved domains. To prevent overfitting to a specific domain, Sharpness-Aware Minimization (SAM) reduces source domain's loss sharpness. Although SAM variants have delivered significant improvements in DG, we highlight that there's still potential for improvement in generalizing to unknown domains through the exploration on data space. This paper introduces an objective rooted in both parameter and data perturbed regions for domain generalization, coined Unknown Domain Inconsistency Minimization (UDIM). UDIM reduces the loss landscape inconsistency between source domain and unknown domains. As unknown domains are inaccessible, these domains are empirically crafted by perturbing instances from the source domain dataset. In particular, by aligning the loss landscape acquired in the source domain to the loss landscape of perturbed domains, we expect to achieve generalization grounded on these flat minima for the unknown domains. Theoretically, we validate that merging SAM optimization with the UDIM objective establishes an upper bound for the true objective of the DG task. In an empirical aspect, UDIM consistently outperforms SAM variants across multiple DG benchmark datasets. Notably, UDIM shows statistically significant improvements in scenarios with more restrictive domain information, underscoring UDIM's generalization capability in unseen domains. Our code is available at https://github.com/SJShin-AI/UDIM.

Continual pre-training has increasingly become the predominant approach for adapting Large Language Models (LLMs) to new domains. This process involves updating the pre-trained LLM with a corpus from a new domain, resulting in a shift in the training distribution. To study the behavior of LLMs during this shift, we measured the model's performance throughout the continual pre-training process. we observed a temporary performance drop at the beginning, followed by a recovery phase, a phenomenon known as the "stability gap," previously noted in vision models classifying new classes. To address this issue and enhance LLM performance within a fixed compute budget, we propose three effective strategies: (1) Continually pre-training the LLM on a subset with a proper size for multiple epochs, resulting in faster performance recovery than pre-training the LLM on a large corpus in a single epoch; (2) Pre-training the LLM only on high-quality sub-corpus, which rapidly boosts domain performance; and (3) Using a data mixture similar to the pre-training data to reduce distribution gap. We conduct various experiments on Llama-family models to validate the effectiveness of our strategies in both medical continual pre-training and instruction tuning. For example, our strategies improve the average medical task performance of the OpenLlama-3B model from 36.2% to 40.7% with only 40% of the original training budget and enhance the average general task performance without causing forgetting. Furthermore, we apply our strategies to the Llama-3-8B model. The resulting model, Llama-3-Physician, achieves the best medical performance among current open-source models, and performs comparably to or even better than GPT-4 on several medical benchmarks. We release our models at https://huggingface.co/YiDuo1999/Llama-3-Physician-8B-Instruct.

Pretraining is the cornerstone of Large Language Models (LLMs), dominating the vast majority of computational budget and data to serve as the primary engine for their capabilities. During pretraining, LLMs acquire foundational knowledge from an unprecedentedly massive and diverse data sources, encompassing a vast array of domains such as general language, mathematics, code, and complex reasoning. In this work, we investigate an interesting geometric question regarding the converged state of pretraining: Does the model converge to a common minimizer across all data sources (e.g., fig:cwa_illustration:close), or merely a minimizer of the summed loss (e.g., fig:cwa_illustration:distant)? We hypothesize that the geometric "closeness" of task-specific minima is intrinsically linked to downstream generalization. We reveal that standard optimizers (e.g., AdamW) often converge to points where task-specific minima are distant from each other. To address this, we propose the Nexus optimizer, which encourages the closeness of these minima by maximizing gradient similarity during optimization. Experiments across models ranging from 130M to 3B parameters, various data mixtures and hyperparameter schedules, show that Nexus significantly boosts downstream performance, despite achieving the same pretraining loss (see fig:demo:benchmark). Notably, on the 3B model, Nexus reduces the out-of-distribution loss by 0.012 and yields up to a 15.0\% accuracy improvement on complex reasoning tasks (e.g., GSM8k). This finding challenges the reliance on pretraining loss as the sole proxy for model evaluation and demonstrates the importance of implicit biases in unlocking downstream generalization.

We present Brainstacks, a modular architecture for continual multi-domain fine-tuning of large language models that packages domain expertise as frozen adapter stacks composing additively on a shared frozen base at inference. Five interlocking components: (1) MoE-LoRA with Shazeer-style noisy top-2 routing across all seven transformer projections under QLoRA 4-bit quantization with rsLoRA scaling; (2) an inner loop performing residual boosting by freezing trained stacks and adding new ones; (3) an outer loop training sequential domain-specific stacks with curriculum-ordered dependencies; (4) null-space projection via randomized SVD constraining new stacks to subspaces orthogonal to prior directions, achieving zero forgetting in isolation; (5) an outcome-based sigmoid meta-router trained on empirically discovered domain-combination targets that selectively weights stacks, enabling cross-domain composition. Two boundary experiments: (6) PSN pretraining on a randomly initialized model; (7) per-domain RL (DPO/GRPO) validating compatibility with post-SFT alignment. Validated on TinyLlama-1.1B (4 domains, 9 stacks) and Gemma 3 12B IT (5 domains, 10 stacks), MoE-LoRA achieves 2.5x faster convergence than parameter-matched single LoRA, residual boosting breaks through the single-stack ceiling, and the routed system recovers generation quality destroyed by ungated stack accumulation. The central finding: the outcome-based router discovers that domain stacks encode transferable cognitive primitives (instruction-following clarity, numerical reasoning, procedural logic, chain-of-thought structure) rather than domain-specific knowledge, with medical prompts routing to chat+math stacks in 97% of cases despite zero medical data in those stacks.

In recent years, graph pre-training has gained significant attention, focusing on acquiring transferable knowledge from unlabeled graph data to improve downstream performance. Despite these recent endeavors, the problem of negative transfer remains a major concern when utilizing graph pre-trained models to downstream tasks. Previous studies made great efforts on the issue of what to pre-train and how to pre-train by designing a variety of graph pre-training and fine-tuning strategies. However, there are cases where even the most advanced "pre-train and fine-tune" paradigms fail to yield distinct benefits. This paper introduces a generic framework W2PGNN to answer the crucial question of when to pre-train (i.e., in what situations could we take advantage of graph pre-training) before performing effortful pre-training or fine-tuning. We start from a new perspective to explore the complex generative mechanisms from the pre-training data to downstream data. In particular, W2PGNN first fits the pre-training data into graphon bases, each element of graphon basis (i.e., a graphon) identifies a fundamental transferable pattern shared by a collection of pre-training graphs. All convex combinations of graphon bases give rise to a generator space, from which graphs generated form the solution space for those downstream data that can benefit from pre-training. In this manner, the feasibility of pre-training can be quantified as the generation probability of the downstream data from any generator in the generator space. W2PGNN offers three broad applications: providing the application scope of graph pre-trained models, quantifying the feasibility of pre-training, and assistance in selecting pre-training data to enhance downstream performance. We provide a theoretically sound solution for the first application and extensive empirical justifications for the latter two applications.

Modern language models are trained on large, unstructured datasets consisting of trillions of tokens and obtained by crawling the web. The unstructured nature makes it difficult to reason about their contents and develop systematic approaches to data curation. In this paper, we unpack monolithic web corpora by developing taxonomies of their contents and organizing them into domains. We introduce WebOrganizer, a framework for organizing web pages in terms of both their topic and format. Using these two complementary notions of domains, we automatically annotate pre-training data by distilling annotations from a large language model into efficient classifiers. This allows us to study how data from different domains should be mixed to improve models on downstream tasks, and we show that we can combine insights about effective topics and formats to further boost performance. We demonstrate that our domain mixing also improves existing methods that select data based on quality. Furthermore, we study and compare how quality-based methods will implicitly change the domain mixture. Overall, our work demonstrates that constructing and mixing domains provides a valuable complement to quality-based data curation methods, opening new avenues for effective and insightful pre-training data curation.

We explore how continued pre-training on domain-specific corpora influences large language models, revealing that training on the raw corpora endows the model with domain knowledge, but drastically hurts its prompting ability for question answering. Taken inspiration from human learning via reading comprehension--practice after reading improves the ability to answer questions based on the learned knowledge--we propose a simple method for transforming raw corpora into reading comprehension texts. Each raw text is enriched with a series of tasks related to its content. Our method, highly scalable and applicable to any pre-training corpora, consistently enhances performance across various tasks in three different domains: biomedicine, finance, and law. Notably, our 7B language model achieves competitive performance with domain-specific models of much larger scales, such as BloombergGPT-50B. Furthermore, we demonstrate that domain-specific reading comprehension texts can improve the model's performance even on general benchmarks, showing the potential to develop a general model across even more domains. Our model, code, and data will be available at https://github.com/microsoft/LMOps.

This paper proposes a novel method for constructing instruction-tuned large language models (LLMs) for finance without instruction data. Traditionally, developing such domain-specific LLMs has been resource-intensive, requiring a large dataset and significant computational power for continual pretraining and instruction tuning. Our study proposes a simpler approach that combines domain-specific continual pretraining with model merging. Given that general-purpose pretrained LLMs and their instruction-tuned LLMs are often publicly available, they can be leveraged to obtain the necessary instruction task vector. By merging this with a domain-specific pretrained vector, we can effectively create instruction-tuned LLMs for finance without additional instruction data. Our process involves two steps: first, we perform continual pretraining on financial data; second, we merge the instruction-tuned vector with the domain-specific pretrained vector. Our experiments demonstrate the successful construction of instruction-tuned LLMs for finance. One major advantage of our method is that the instruction-tuned and domain-specific pretrained vectors are nearly independent. This independence makes our approach highly effective. The Japanese financial instruction-tuned LLMs we developed in this study are available at https://huggingface.co/pfnet/nekomata-14b-pfn-qfin-inst-merge.

Domain generalization (DG) aims to adapt a model using one or multiple source domains to ensure robust performance in unseen target domains. Recently, Parameter-Efficient Fine-Tuning (PEFT) of foundation models has shown promising results in the context of DG problem. Nevertheless, existing PEFT methods still struggle to strike a balance between preserving generalizable components of the pre-trained model and learning task-specific features. To gain insights into the distribution of generalizable components, we begin by analyzing the pre-trained weights through the lens of singular value decomposition. Building on these insights, we introduce Singular Value Decomposed Minor Components Adaptation (SoMA), an approach that selectively tunes minor singular components while keeping the residual parts frozen. SoMA effectively retains the generalization ability of the pre-trained model while efficiently acquiring task-specific skills. Moreover, we freeze domain-generalizable blocks and employ an annealing weight decay strategy, thereby achieving an optimal balance in the delicate trade-off between generalizability and discriminability. SoMA attains state-of-the-art results on multiple benchmarks that span both domain generalized semantic segmentation to domain generalized object detection. In addition, our methods introduce no additional inference overhead or regularization loss, maintain compatibility with any backbone or head, and are designed to be versatile, allowing easy integration into a wide range of tasks.

We consider two problems of NMT domain adaptation using meta-learning. First, we want to reach domain robustness, i.e., we want to reach high quality on both domains seen in the training data and unseen domains. Second, we want our systems to be adaptive, i.e., making it possible to finetune systems with just hundreds of in-domain parallel sentences. We study the domain adaptability of meta-learning when improving the domain robustness of the model. In this paper, we propose a novel approach, RMLNMT (Robust Meta-Learning Framework for Neural Machine Translation Domain Adaptation), which improves the robustness of existing meta-learning models. More specifically, we show how to use a domain classifier in curriculum learning and we integrate the word-level domain mixing model into the meta-learning framework with a balanced sampling strategy. Experiments on EnglishrightarrowGerman and EnglishrightarrowChinese translation show that RMLNMT improves in terms of both domain robustness and domain adaptability in seen and unseen domains. Our source code is available at https://github.com/lavine-lmu/RMLNMT.

Recently, extensive deep learning architectures and pretraining strategies have been explored to support downstream protein applications. Additionally, domain-specific models incorporating biological knowledge have been developed to enhance performance in specialized tasks. In this work, we introduce Protap, a comprehensive benchmark that systematically compares backbone architectures, pretraining strategies, and domain-specific models across diverse and realistic downstream protein applications. Specifically, Protap covers five applications: three general tasks and two novel specialized tasks, i.e., enzyme-catalyzed protein cleavage site prediction and targeted protein degradation, which are industrially relevant yet missing from existing benchmarks. For each application, Protap compares various domain-specific models and general architectures under multiple pretraining settings. Our empirical studies imply that: (i) Though large-scale pretraining encoders achieve great results, they often underperform supervised encoders trained on small downstream training sets. (ii) Incorporating structural information during downstream fine-tuning can match or even outperform protein language models pretrained on large-scale sequence corpora. (iii) Domain-specific biological priors can enhance performance on specialized downstream tasks. Code and datasets are publicly available at https://github.com/Trust-App-AI-Lab/protap.

Traditional cross-domain tasks, including domain adaptation and domain generalization, rely heavily on training model by source domain data. With the recent advance of vision-language models (VLMs), viewed as natural source models, the cross-domain task changes to directly adapt the pre-trained source model to arbitrary target domains equipped with prior domain knowledge, and we name this task Adaptive Domain Generalization (ADG). However, current cross-domain datasets have many limitations, such as unrealistic domains, unclear domain definitions, and the inability to fine-grained domain decomposition, which drives us to establish a novel dataset DomainVerse for ADG. Benefiting from the introduced hierarchical definition of domain shifts, DomainVerse consists of about 0.5 million images from 390 fine-grained realistic domains. With the help of the constructed DomainVerse and VLMs, we propose two methods called Domain CLIP and Domain++ CLIP for tuning-free adaptive domain generalization. Extensive and comprehensive experiments demonstrate the significance of the dataset and the effectiveness of the proposed methods.

The problem of domain generalization is to learn from multiple training domains, and extract a domain-agnostic model that can then be applied to an unseen domain. Domain generalization (DG) has a clear motivation in contexts where there are target domains with distinct characteristics, yet sparse data for training. For example recognition in sketch images, which are distinctly more abstract and rarer than photos. Nevertheless, DG methods have primarily been evaluated on photo-only benchmarks focusing on alleviating the dataset bias where both problems of domain distinctiveness and data sparsity can be minimal. We argue that these benchmarks are overly straightforward, and show that simple deep learning baselines perform surprisingly well on them. In this paper, we make two main contributions: Firstly, we build upon the favorable domain shift-robust properties of deep learning methods, and develop a low-rank parameterized CNN model for end-to-end DG learning. Secondly, we develop a DG benchmark dataset covering photo, sketch, cartoon and painting domains. This is both more practically relevant, and harder (bigger domain shift) than existing benchmarks. The results show that our method outperforms existing DG alternatives, and our dataset provides a more significant DG challenge to drive future research.

Continued pretraining offers a promising solution for adapting foundation models to a new target domain. However, in specialized domains, available datasets are often very small, limiting the applicability of SSL methods developed for large-scale pretraining and making hyperparameter search infeasible. In addition, pretrained models are usually released as backbone-weights only, lacking important information to continue pretraining. We propose to bridge this gap with DIET-CP, a simple continued pretraining strategy, where any strong foundation model can be steered towards the new data distribution of interest. DIET-CP relies on a very simple objective, requires no labels, and introduces no more hyperparameters than supervised finetuning. It is stable across data modalities and backbone choices, while providing a significant performance boost for state-of-the-art models such as DINOv3 using only 1000 images.

Generic pre-trained neural networks may struggle to produce good results in specialized domains like finance and insurance. This is due to a domain mismatch between training data and downstream tasks, as in-domain data are often scarce due to privacy constraints. In this work, we compare different pre-training strategies for LayoutLM. We show that using domain-relevant documents improves results on a named-entity recognition (NER) problem using a novel dataset of anonymized insurance-related financial documents called Payslips. Moreover, we show that we can achieve competitive results using a smaller and faster model.

Unsupervised domain adaptation has recently emerged as an effective paradigm for generalizing deep neural networks to new target domains. However, there is still enormous potential to be tapped to reach the fully supervised performance. In this paper, we present a novel active learning strategy to assist knowledge transfer in the target domain, dubbed active domain adaptation. We start from an observation that energy-based models exhibit free energy biases when training (source) and test (target) data come from different distributions. Inspired by this inherent mechanism, we empirically reveal that a simple yet efficient energy-based sampling strategy sheds light on selecting the most valuable target samples than existing approaches requiring particular architectures or computation of the distances. Our algorithm, Energy-based Active Domain Adaptation (EADA), queries groups of target data that incorporate both domain characteristic and instance uncertainty into every selection round. Meanwhile, by aligning the free energy of target data compact around the source domain via a regularization term, domain gap can be implicitly diminished. Through extensive experiments, we show that EADA surpasses state-of-the-art methods on well-known challenging benchmarks with substantial improvements, making it a useful option in the open world. Code is available at https://github.com/BIT-DA/EADA.

In this paper, we tackle the problem of domain shift. Most existing methods perform training on multiple source domains using a single model, and the same trained model is used on all unseen target domains. Such solutions are sub-optimal as each target domain exhibits its own specialty, which is not adapted. Furthermore, expecting single-model training to learn extensive knowledge from multiple source domains is counterintuitive. The model is more biased toward learning only domain-invariant features and may result in negative knowledge transfer. In this work, we propose a novel framework for unsupervised test-time adaptation, which is formulated as a knowledge distillation process to address domain shift. Specifically, we incorporate Mixture-of-Experts (MoE) as teachers, where each expert is separately trained on different source domains to maximize their specialty. Given a test-time target domain, a small set of unlabeled data is sampled to query the knowledge from MoE. As the source domains are correlated to the target domains, a transformer-based aggregator then combines the domain knowledge by examining the interconnection among them. The output is treated as a supervision signal to adapt a student prediction network toward the target domain. We further employ meta-learning to enforce the aggregator to distill positive knowledge and the student network to achieve fast adaptation. Extensive experiments demonstrate that the proposed method outperforms the state-of-the-art and validates the effectiveness of each proposed component. Our code is available at https://github.com/n3il666/Meta-DMoE.

Recent works have demonstrated the effectiveness of self-alignment in which a large language model is, by itself, aligned to follow general instructions through the automatic generation of instructional data using a handful of human-written seeds. Instead of general alignment, in this work, we focus on self-alignment for expert domain specialization (e.g., biomedicine), discovering it to be very effective for improving zero-shot and few-shot performance in target domains of interest. As a preliminary, we first present the benchmark results of existing aligned models within a specialized domain, which reveals the marginal effect that "generic" instruction-following training has on downstream expert domains' performance. To remedy this, we explore self-specialization that leverages domain-specific unlabelled data and a few labeled seeds for the self-alignment process. When augmented with retrieval to reduce hallucination and enhance concurrency of the alignment, self-specialization offers an effective (and efficient) way of "carving out" an expert model out of a "generalist", pre-trained LLM where different domains of expertise are originally combined in a form of "superposition". Our experimental results on a biomedical domain show that our self-specialized model (30B) outperforms its base model, MPT-30B by a large margin and even surpasses larger popular models based on LLaMA-65B, highlighting its potential and practicality for specialization, especially considering its efficiency in terms of data and parameters.

Unsupervised domain adaptation leverages abundant labeled data from various source domains to generalize onto unlabeled target data. Prior research has primarily focused on learning domain-invariant features across the source and target domains. However, these methods often require training a model using source domain data, which is time-consuming and can limit model usage for applications with different source data. This paper introduces a simple framework that utilizes the impressive generalization capabilities of Large Language Models (LLMs) for target data annotation without the need of source model training, followed by a novel similarity-based knowledge distillation loss. Our extensive experiments on cross-domain text classification reveal that our framework achieves impressive performance, specifically, 2.44\% accuracy improvement when compared to the SOTA method.

Large language models (LLMs) already excel at writing code in high-resource languages such as Python and JavaScript, yet stumble on low-resource languages that remain essential to science and engineering. Besides the obvious shortage of pre-training data, post-training itself is a bottleneck: every new language seems to require new datasets, test harnesses, and reinforcement-learning (RL) infrastructure. We introduce Agnostics, a language-agnostic post-training pipeline that eliminates this per-language engineering. The key idea is to judge code solely by its externally observable behavior, so a single verifier can test solutions written in any language. Concretely, we (i) use an LLM to rewrite existing unit-test datasets into an I/O format, (ii) supply a short configuration that tells the verifier how to compile and run a target language, and (iii) apply reinforcement learning with verifiable rewards (RLVR) in a robust code execution environment. Applied to five low-resource languages--Lua, Julia, R, OCaml, and Fortran--Agnostics (1) improves Qwen-3 4B to performance that rivals other 16B-70B open-weight models; (2) scales cleanly to larger and diverse model families (Qwen-3 8B, DeepSeek Coder 6.7B Instruct, Phi 4 Mini); and (3) for {le} 16B parameter models, sets new state-of-the-art pass@1 results on MultiPL-E and a new multi-language version LiveCodeBench that we introduce. We will release the language-agnostic training datasets (Ag-MBPP-X, Ag-Codeforces-X, Ag-LiveCodeBench-X), training code, and ready-to-use configurations, making RL post-training in any programming language as simple as editing a short YAML file.

Domain-specific supervised fine-tuning (SFT) often improves in-domain performance at the cost of degrading a model's general capabilities. We view this degradation through two practical gaps in domain SFT: a supervision-compatibility gap, where domain targets differ in style and reasoning format from the original model's natural responses, and a trajectory-preservation gap, where teacher-forced SFT optimizes fixed target tokens without constraining the model's behavior on its own generated prefixes. This process fails to preserve the model's original behavior. We propose RAFT (Data Refinement and Adaptive Distillation for Domain Fine-Tuning with Alleviated Forgetting), a two-stage framework that addresses both factors. First, RAFT constructs model-compatible supervision through self-conditioned rewriting, semantic filtering, and answer fusion. Second, RAFT performs Answer-Conditioned On-Policy Distillation, where the original instruction-tuned model provides soft targets on student-generated trajectories while being conditioned on the fused answer as helpful context. We further introduce top-K temperature distillation and EMA-based adaptive loss balancing to stabilize the domain-general trade-off. Across three instruction-tuned backbones and five domains, RAFT improves average domain accuracy by 23.2% over standard SFT, while recovering part of the SFT-induced degradation on MS-Bench and IFEval, with relative improvements of 18.2% and 10.2%, respectively. These results show that coupling data refinement with trajectory-level preservation provides an effective recipe for domain fine-tuning with alleviated forgetting.

Curriculum learning has shown promise in improving training efficiency and generalization in various machine learning domains, yet its potential in pretraining language models remains underexplored, prompting our work as the first systematic investigation in this area. We experimented with different settings, including vanilla curriculum learning, pacing-based sampling, and interleaved curricula-guided by six difficulty metrics spanning linguistic and information-theoretic perspectives. We train models under these settings and evaluate their performance on eight diverse benchmarks. Our experiments reveal that curriculum learning consistently improves convergence in early and mid-training phases, and can yield lasting gains when used as a warmup strategy with up to 3.5% improvement. Notably, we identify compression ratio, lexical diversity, and readability as effective difficulty signals across settings. Our findings highlight the importance of data ordering in large-scale pretraining and provide actionable insights for scalable, data-efficient model development under realistic training scenarios.

Continual learning has emerged as an important research direction due to the infeasibility of retraining large language models (LLMs) from scratch in the event of new data availability. Of great interest is the domain-adaptive pre-training (DAPT) paradigm, which focuses on continually training a pre-trained language model to adapt it to a domain it was not originally trained on. In this work, we evaluate the feasibility of DAPT in a low-resource setting, namely the Nepali language. We use synthetic data to continue training Llama 3 8B to adapt it to the Nepali language in a 4-bit QLoRA setting. We evaluate the adapted model on its performance, forgetting, and knowledge acquisition. We compare the base model and the final model on their Nepali generation abilities, their performance on popular benchmarks, and run case-studies to probe their linguistic knowledge in Nepali. We see some unsurprising forgetting in the final model, but also surprisingly find that increasing the number of shots during evaluation yields better percent increases in the final model (as high as 19.29% increase) compared to the base model (4.98%), suggesting latent retention. We also explore layer-head self-attention heatmaps to establish dependency resolution abilities of the final model in Nepali.

Large Language Models have demonstrated remarkable progress in general-purpose capabilities and can achieve strong performance in specific domains through fine-tuning on domain-specific data. However, acquiring high-quality data for target domains remains a significant challenge. Existing data synthesis approaches follow a deductive paradigm, heavily relying on explicit domain descriptions expressed in natural language and careful prompt engineering, limiting their applicability in real-world scenarios where domains are difficult to describe or formally articulate. In this work, we tackle the underexplored problem of domain-specific data synthesis through an inductive paradigm, where the target domain is defined only through a set of reference examples, particularly when domain characteristics are difficult to articulate in natural language. We propose a novel framework, DOMINO, that learns a minimal sufficient domain representation from reference samples and leverages it to guide the generation of domain-aligned synthetic data. DOMINO integrates prompt tuning with a contrastive disentanglement objective to separate domain-level patterns from sample-specific noise, mitigating overfitting while preserving core domain characteristics. Theoretically, we prove that DOMINO expands the support of the synthetic data distribution, ensuring greater diversity. Empirically, on challenging coding benchmarks where domain definitions are implicit, fine-tuning on data synthesized by DOMINO improves Pass@1 accuracy by up to 4.63\% over strong, instruction-tuned backbones, demonstrating its effectiveness and robustness. This work establishes a new paradigm for domain-specific data synthesis, enabling practical and scalable domain adaptation without manual prompt design or natural language domain specifications.

Pre-trained language models have been successful in many knowledge-intensive NLP tasks. However, recent work has shown that models such as BERT are not ``structurally ready'' to aggregate textual information into a [CLS] vector for dense passage retrieval (DPR). This ``lack of readiness'' results from the gap between language model pre-training and DPR fine-tuning. Previous solutions call for computationally expensive techniques such as hard negative mining, cross-encoder distillation, and further pre-training to learn a robust DPR model. In this work, we instead propose to fully exploit knowledge in a pre-trained language model for DPR by aggregating the contextualized token embeddings into a dense vector, which we call agg*. By concatenating vectors from the [CLS] token and agg*, our Aggretriever model substantially improves the effectiveness of dense retrieval models on both in-domain and zero-shot evaluations without introducing substantial training overhead. Code is available at https://github.com/castorini/dhr

A key challenge in Domain Generalization (DG) is preventing overfitting to source domains, which can be mitigated by finding flatter minima in the loss landscape. In this work, we propose Quantization-aware Training for Domain Generalization (QT-DoG) and demonstrate that weight quantization effectively leads to flatter minima in the loss landscape, thereby enhancing domain generalization. Unlike traditional quantization methods focused on model compression, QT-DoG exploits quantization as an implicit regularizer by inducing noise in model weights, guiding the optimization process toward flatter minima that are less sensitive to perturbations and overfitting. We provide both an analytical perspective and empirical evidence demonstrating that quantization inherently encourages flatter minima, leading to better generalization across domains. Moreover, with the benefit of reducing the model size through quantization, we demonstrate that an ensemble of multiple quantized models further yields superior accuracy than the state-of-the-art DG approaches with no computational or memory overheads. Code is released at: https://saqibjaved1.github.io/QT_DoG/.

The recent rapid progress in pre-training Large Language Models has relied on using self-supervised language modeling objectives like next token prediction or span corruption. On the other hand, Machine Translation Systems are mostly trained using cross-lingual supervision that requires aligned data between source and target languages. We demonstrate that pre-training Large Language Models on a mixture of a self-supervised Language Modeling objective and the supervised Machine Translation objective, therefore including cross-lingual parallel data during pre-training, yields models with better in-context learning abilities. As pre-training is a very resource-intensive process and a grid search on the best mixing ratio between the two objectives is prohibitively expensive, we propose a simple yet effective strategy to learn it during pre-training.

Clinical deployment of automated brain MRI analysis faces a fundamental challenge: clinical data is heterogeneous and noisy, and high-quality labels are prohibitively costly to obtain. Self-supervised learning (SSL) can address this by leveraging the vast amounts of unlabeled data produced in clinical workflows to train robust foundation models that adapt out-of-domain with minimal supervision. However, the development of foundation models for brain MRI has been limited by small pretraining datasets and in-domain benchmarking focused on high-quality, research-grade data. To address this gap, we organized the FOMO25 challenge as a satellite event at MICCAI 2025. FOMO25 provided participants with a large pretraining dataset, FOMO60K, and evaluated models on data sourced directly from clinical workflows in few-shot and out-of-domain settings. Tasks covered infarct classification, meningioma segmentation, and brain age regression, and considered both models trained on FOMO60K (method track) and any data (open track). Nineteen foundation models from sixteen teams were evaluated using a standardized containerized pipeline. Results show that (a) self-supervised pretraining improves generalization on clinical data under domain shift, with the strongest models trained out-of-domain surpassing supervised baselines trained in-domain. (b) No single pretraining objective benefits all tasks: MAE favors segmentation, hybrid reconstruction-contrastive objectives favor classification, and (c) strong performance was achieved by small pretrained models, and improvements from scaling model size and training duration did not yield reliable benefits.

Aligning large language models (LLMs) to human preferences is challenging in domains where preference data is unavailable. We address the problem of learning reward models for such target domains by leveraging feedback collected from simpler source domains, where human preferences are easier to obtain. Our key insight is that, while domains may differ significantly, human preferences convey domain-agnostic concepts that can be effectively captured by a reward model. We propose \method, a framework that trains domain-invariant reward models by optimizing a dual loss: a domain loss that minimizes the divergence between source and target distribution, and a source loss that optimizes preferences on the source domain. We show \method is a general approach that we evaluate and analyze across 4 distinct settings: (1) Cross-lingual transfer (accuracy: 0.621 rightarrow 0.661), (2) Clean-to-noisy (accuracy: 0.671 rightarrow 0.703), (3) Few-shot-to-full transfer (accuracy: 0.845 rightarrow 0.920), and (4) Simple-to-complex tasks transfer (correlation: 0.508 rightarrow 0.556). Our code, models and data are available at https://github.com/portal-cornell/dial.